PDB entry 3dab
View 3dab on RCSB PDB site
Description: Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
Class: cell cycle
Keywords: MDMX, MDM4, HDMX, HDM4, MDM-4, MDM-X, MDM2, HDM2, P53, tumor, nucleus, oncogene, apoptosis, cell cycle, disease mutation, DNA-binding, transcription
Deposited on
2008-05-29, released
2008-09-02
The last revision prior to the SCOPe 2.02 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.2
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: mdm4 protein
Species: Homo sapiens [TaxId:9606]
Gene: mdm4, mdmx
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3daba_ - Chain 'B':
Compound: Cellular tumor antigen p53
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'C':
Compound: mdm4 protein
Species: Homo sapiens [TaxId:9606]
Gene: mdm4, mdmx
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3dabc_ - Chain 'D':
Compound: Cellular tumor antigen p53
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'E':
Compound: mdm4 protein
Species: Homo sapiens [TaxId:9606]
Gene: mdm4, mdmx
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3dabe_ - Chain 'F':
Compound: Cellular tumor antigen p53
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'G':
Compound: mdm4 protein
Species: Homo sapiens [TaxId:9606]
Gene: mdm4, mdmx
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d3dabg_ - Chain 'H':
Compound: Cellular tumor antigen p53
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3dabA (A:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtlat
Sequence, based on observed residues (ATOM records): (download)
>3dabA (A:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtl
- Chain 'B':
No sequence available.
- Chain 'C':
Sequence, based on SEQRES records: (download)
>3dabC (C:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtlat
Sequence, based on observed residues (ATOM records): (download)
>3dabC (C:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlv
- Chain 'D':
No sequence available.
- Chain 'E':
Sequence, based on SEQRES records: (download)
>3dabE (E:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtlat
Sequence, based on observed residues (ATOM records): (download)
>3dabE (E:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlv
- Chain 'F':
No sequence available.
- Chain 'G':
Sequence, based on SEQRES records: (download)
>3dabG (G:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtlat
Sequence, based on observed residues (ATOM records): (download)
>3dabG (G:)
iqinqvrpklpllkilhaagaqgemftvkevmhylgqyimvkqlydqqeqhmvycggdll
gellgrqsfsvkdpsplydmlrknlvtl
- Chain 'H':
No sequence available.