PDB entry 3d4u

View 3d4u on RCSB PDB site
Description: Bovine thrombin-activatable fibrinolysis inhibitor (TAFIa) in complex with tick-derived carboxypeptidase inhibitor.
Class: hydrolase/hydrolase inhibitor
Keywords: protease-inhibitor complex, Carboxypeptidase, Glycoprotein, Hydrolase, Metal-binding, Metalloprotease, Protease, Secreted, Zymogen, Blood coagulation, Fibrinolysis, Metalloenzyme inhibitor, Metalloprotease inhibitor, HYDROLASE-HYDROLASE INHIBITOR COMPLEX
Deposited on 2008-05-15, released 2008-08-19
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.156
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carboxypeptidase B2
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3d4ua_
  • Chain 'B':
    Compound: carboxypeptidase inhibitor
    Species: Rhipicephalus bursa [TaxId:67831]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d3d4ub1, d3d4ub2
  • Heterogens: ZN, ACT, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3d4uA (A:)
asssyyeqyhslneiyswievmterypdmvekihigssyekyplyvlkvskkeqraknam
widcgiharewispafclwfvgsvtyyygkekmhtnllkhmdfyimpvvnvdgydytwkk
drmwrknrslheknacvgtdlnrnfaskhwcgegasssscseiycgtypesepevkavad
flrrnikhikayismhsysqkivfpysysrsrskdheelslvareavfamenihrniryt
hgsgseslylapggsddwiydlgikysftfelrdkgkygfllpesyirptcsealvavak
iashvvknv

    Sequence, based on observed residues (ATOM records): (download) 
    >3d4uA (A:)
syyeqyhslneiyswievmterypdmvekihigssyekyplyvlkvskknamwidcgiha
rewispafclwfvgsvtyyygknllkhmdfyimpvvnvdgydytwkkdrmwrknrslhek
nacvgtdlnrnfaskhwcgegasssscseiycgtypesepevkavadflrrnikhikayi
smhsysqkivfpysysrsrskdheelslvareavfamenihrnirythgsgseslylapg
gsddwiydlgikysftfelrdkgkygfllpesyirptcsealvavakiashvvknv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3d4uB (B:)
necvskgfgclpqsdcpqearlsyggcstvccdlskltgckgkggecnpldrqckelqae
sascgkgqkccvwl