PDB entry 3cxv

View 3cxv on RCSB PDB site
Description: Crystal structure of the Cytochrome P450 CYP121 A233G mutant from Mycobacterium tuberculosis
Class: oxidoreductase
Keywords: cytochrome P450, CYP121, Mycobacterium tuberculosis, Cytoplasm, Heme, Iron, Metal-binding, Monooxygenase, Oxidoreductase
Deposited on 2008-04-25, released 2008-09-23
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-01-20, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.167
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome P450 121
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Gene: cyp121
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A514 (Start-395)
      • engineered (232)
    Domains in SCOPe 2.02: d3cxva_
  • Heterogens: SO4, HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cxvA (A:)
mtatvllevpfsargdripdavaelrtrepirkvrtitgaeawlvssyalctqvledrrf
smketaaagaprlnaltvppevvnnmgniadaglrkavmkaitpkapgleqflrdtansl
ldnlitegapadlrndfadplatalhckvlgipqedgpklfrslsiafmssadpipaaki
nwdrdieymagilenpnittglmgelsrlrkdpayshvsdelfatigvtffgggvistgs
flttalisliqrpqlrnllhekpelipagveellrinlsfadglprlatadiqvgdvlvr
kgelvlvlleganfdpehfpnpgsieldrpnptshlafgrgqhfcpgsalgrrhaqigie
allkkmpgvdlavpidqlvwrtrfqrriperlpvlw

    Sequence, based on observed residues (ATOM records): (download) 
    >3cxvA (A:)
tatvllevpfsargdripdavaelrtrepirkvrtitgaeawlvssyalctqvledrrfs
mketaaagaprlnaltvppevvnnmgniadaglrkavmkaitpkapgleqflrdtansll
dnlitegapadlrndfadplatalhckvlgipqedgpklfrslsiafmssadpipaakin
wdrdieymagilenpnittglmgelsrlrkdpayshvsdelfatigvtffgggvistgsf
lttalisliqrpqlrnllhekpelipagveellrinlsfadglprlatadiqvgdvlvrk
gelvlvlleganfdpehfpnpgsieldrpnptshlafgrgqhfcpgsalgrrhaqigiea
llkkmpgvdlavpidqlvwrtrfqrriperlpvlw