PDB entry 3cri
View 3cri on RCSB PDB site
Description: Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala
Class: hormone
Keywords: crystal packing, Acetylation, Angiogenesis, Developmental protein, Differentiation, Growth factor, Heparin-binding, Mitogen, Polymorphism, HORMONE
Deposited on
2008-04-07, released
2009-02-17
The last revision prior to the SCOPe 2.06 freeze date was dated
2010-01-05, with a file datestamp of
2009-12-31.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.199
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (86-87)
- engineered (106)
Domains in SCOPe 2.06: d3cria1, d3cria2 - Chain 'B':
Compound: heparin-binding growth factor 1
Species: Homo sapiens [TaxId:9606]
Gene: FGF1, FGFA
Database cross-references and differences (RAF-indexed):
- Uniprot P05230
- engineered (86-87)
- engineered (106)
Domains in SCOPe 2.06: d3crib1, d3crib2 - Heterogens: SO4, FMT, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3criA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpnsnclflerleenhyntyiskahaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3criA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevyi
kstetgqylamdtdgllygsqtpnsnclflerleenhyntyiskahaeknwfvglkkngs
ckrgprthygqkailflplpv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>3criB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgev
yikstetgqylamdtdgllygsqtpnsnclflerleenhyntyiskahaeknwfvglkkn
gsckrgprthygqkailflplpvssd
Sequence, based on observed residues (ATOM records): (download)
>3criB (B:)
hhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqlqlsaesvgevy
ikstetgqylamdtdgllygsqtpnsnclflerleenhyntyiskahaeknwfvglkkng
sckrgprthygqkailflplpv