PDB entry 3cok

View 3cok on RCSB PDB site
Description: Crystal structure of PLK4 kinase
Class: transferase
Keywords: PLK4, Polo-like kinase 4, SAK, STK18, PSI, structural genomics, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, NYSGXRC, ATP-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Serine/threonine-protein kinase, Transferase
Deposited on 2008-03-28, released 2008-04-15
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-06-09, with a file datestamp of 2009-06-05.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.211
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein kinase PLK4
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK4, SAK, STK18
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00444 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.02: d3coka_
  • Chain 'B':
    Compound: Serine/threonine-protein kinase PLK4
    Species: Homo sapiens [TaxId:9606]
    Gene: PLK4, SAK, STK18
    Database cross-references and differences (RAF-indexed):
    • Uniprot O00444 (2-End)
      • expression tag (0-1)
    Domains in SCOPe 2.02: d3cokb_
  • Heterogens: SO4, ANP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cokA (A:)
slatcigekiedfkvgnllgkgsfagvyraesihtglevaikmidkkamykagmvqrvqn
evkihcqlkhpsilelynyfedsnyvylvlemchngemnrylknrvkpfsenearhfmhq
iitgmlylhshgilhrdltlsnllltrnmnikiadfglatqlkmphekhytlcgtpnyis
peiatrsahglesdvwslgcmfytlligrppfdtdtvkntlnkvvladyempsflsieak
dlihqllrrnpadrlslssvldhpfmsrnsstkskdeg

    Sequence, based on observed residues (ATOM records): (download) 
    >3cokA (A:)
slatcigekiedfkvgnllgkgsfagvyraesihtglevaikmidkkamykagmvqrvqn
evkihcqlkhpsilelynyfedsnyvylvlemchngemnrylknrvkpfsenearhfmhq
iitgmlylhshgilhrdltlsnllltrnmnikiadfglatqlkesdvwslgcmfytllig
rppfdtdtvkvvladyempsflsieakdlihqllrrnpadrlslssvldhpfms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3cokB (B:)
slatcigekiedfkvgnllgkgsfagvyraesihtglevaikmidkkamykagmvqrvqn
evkihcqlkhpsilelynyfedsnyvylvlemchngemnrylknrvkpfsenearhfmhq
iitgmlylhshgilhrdltlsnllltrnmnikiadfglatqlkmphekhytlcgtpnyis
peiatrsahglesdvwslgcmfytlligrppfdtdtvkntlnkvvladyempsflsieak
dlihqllrrnpadrlslssvldhpfmsrnsstkskdeg

    Sequence, based on observed residues (ATOM records): (download) 
    >3cokB (B:)
slatcigekiedfkvgnllgkgsfagvyraesihtglevaikmidkkamykagmvqrvqn
evkihcqlkhpsilelynyfedsnyvylvlemchngemnrylknrvkpfsenearhfmhq
iitgmlylhshgilhrdltlsnllltrnmnikiadfglatqlklesdvwslgcmfytlli
grppfntlnkvvladyempsflsieakdlihqllrrnpadrlslssvldhpfms