PDB entry 3cjg
View 3cjg on RCSB PDB site
Description: Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine
Class: transferase
Keywords: Vascular endothelial growth factor receptor 2. vegfr-2, kinase insert domain receptor, protein-tyrosine kinase receptor flk-1, Angiogenesis, ATP-binding, Developmental protein, Differentiation, Glycoprotein, Host-virus interaction, Immunoglobulin domain, Membrane, Nucleotide-binding, Phosphoprotein, Transferase, Transmembrane, Tyrosine-protein kinase
Deposited on
2008-03-12, released
2008-10-07
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.209
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Vascular endothelial growth factor receptor 2
Species: HOMO SAPIENS
Gene: KDR, FLK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d3cjga_ - Heterogens: SO4, KIM, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>3cjgA (A:)
mdpdelpldehcerlpydaskwefprdrlnlgkplgrgafgqvieadafgidktatcrtv
avkmlkegathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgnls
tylrskrnefvpykdlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillsek
nvvkicdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvllweif
slgaspypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfselveh
lgnllqana
Sequence, based on observed residues (ATOM records): (download)
>3cjgA (A:)
hcerlpydaskwefprdrlnlgkplgrgqvieadafgidktatcrtvavkmlkegathse
hralmselkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnefvpy
kdlykdfltlehlicysfqvakgmeflasrkcihrdlaarnillseknvvkicdfglard
iplkwmapetifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlkegtrmr
apdyttpemyqtmldcwhgepsqrptfselvehlgnllqana