PDB entry 3cir

View 3cir on RCSB PDB site
Description: E. coli Quinol fumarate reductase FrdA T234A mutation
Class: Oxidoreductase
Keywords: electron transport, Tricarboxylic acid cycle, Oxidoreductase
Deposited on 2008-03-11, released 2008-04-01
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.65 Å
R-factor: 0.261
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fumarate reductase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Gene: FrdA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00363 (0-End)
      • engineered (234)
    Domains in SCOPe 2.02: d3cira1, d3cira2, d3cira3
  • Chain 'B':
    Compound: Fumarate reductase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Gene: frdB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3cirb1, d3cirb2
  • Chain 'C':
    Compound: Fumarate reductase subunit C
    Species: Escherichia coli [TaxId:562]
    Gene: frdC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3circ1
  • Chain 'D':
    Compound: Fumarate reductase subunit D
    Species: Escherichia coli [TaxId:562]
    Gene: frdD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3cird1
  • Chain 'M':
    Compound: Fumarate reductase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Gene: FrdA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00363 (0-End)
      • engineered (234)
    Domains in SCOPe 2.02: d3cirm1, d3cirm2, d3cirm3
  • Chain 'N':
    Compound: Fumarate reductase iron-sulfur subunit
    Species: Escherichia coli [TaxId:562]
    Gene: frdB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3cirn1, d3cirn2
  • Chain 'O':
    Compound: Fumarate reductase subunit C
    Species: Escherichia coli [TaxId:562]
    Gene: frdC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3ciro1
  • Chain 'P':
    Compound: Fumarate reductase subunit D
    Species: Escherichia coli [TaxId:562]
    Gene: frdD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3cirp1
  • Heterogens: FES, F3S, SF4, FAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3cirA (A:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaeggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhpaglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkittlppakrvyggeadaadkaeaankkeka
ng

    Sequence, based on observed residues (ATOM records): (download) 
    >3cirA (A:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaeggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhpaglpgs
gilmtegcrgeggirdkvsqafwhewrkgntistprgyldlrhlgekklherlpficela
kayvgvdpvkepipvrptahytmggietdqncetrikglfavgecssvglhganrlgsns
laelvvfgrlageqateraatagngneaaieaqaagveqrlkdlvnqdggenwakirdem
glameegcgiyrtpelmqktidklaelqerfkrvritdtssvfntdllytielghglnva
ecmahsamarkesrgahqrldegcterddvnflkhtlafrdadgttrleysdvkittlpp
a

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirB (B:)
aemknlkievvrynpevdtaphsafyevpydattslldalgyikdnlapdlsyrwscrma
icgscgmmvnnvpklacktflrdytdgmkvealanfpierdlvvdmthfiesleaikpyi
ignsrtadqgtniqtpaqmakyhqfsgcincglcyaacpqfglnpefigpaaitlahryn
edsrdhgkkermaqlnsqngvwsctfvgycsevcpkhvdpaaaiqqgkvesskdfliatl
kpr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirC (C:)
ttkrkpyvrpmtstwwkklpfyrfymlregtavpavwfsielifglfalkngpeawagfv
dflqnpviviinlitlaaallhtktwfelapkaaniivkdekmgpepiikslwavtvvat
ivilfvalyw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirD (D:)
minpnpkrsdepvfwglfgaggmwsaiiapvmillvgillplglfpgdalsyervlafaq
sfigrvflflmivlplwcglhrmhhamhdlkihvpagkwvfyglaailtvvtligvvti

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >3cirM (M:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaeggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhpaglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkittlppakrvyggeadaadkaeaankkeka
ng

    Sequence, based on observed residues (ATOM records): (download) 
    >3cirM (M:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaeggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhpaglpgs
gilmtegcrdkvsqafwhewrkgntiskklheficelakaypvrptahytmggietdqnc
etrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagngneaaiea
qaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidklaelqerfk
rvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegcterddvnf
lkhtlafrdadgttrleysdvkit

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirN (N:)
aemknlkievvrynpevdtaphsafyevpydattslldalgyikdnlapdlsyrwscrma
icgscgmmvnnvpklacktflrdytdgmkvealanfpierdlvvdmthfiesleaikpyi
ignsrtadqgtniqtpaqmakyhqfsgcincglcyaacpqfglnpefigpaaitlahryn
edsrdhgkkermaqlnsqngvwsctfvgycsevcpkhvdpaaaiqqgkvesskdfliatl
kpr

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirO (O:)
ttkrkpyvrpmtstwwkklpfyrfymlregtavpavwfsielifglfalkngpeawagfv
dflqnpviviinlitlaaallhtktwfelapkaaniivkdekmgpepiikslwavtvvat
ivilfvalyw

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3cirP (P:)
minpnpkrsdepvfwglfgaggmwsaiiapvmillvgillplglfpgdalsyervlafaq
sfigrvflflmivlplwcglhrmhhamhdlkihvpagkwvfyglaailtvvtligvvti