PDB entry 3chp

View 3chp on RCSB PDB site
Description: Crystal structure of leukotriene a4 hydrolase in complex with (3S)-3-amino-4-oxo-4-[(4-phenylmethoxyphenyl)amino]butanoic acid
Class: hydrolase
Keywords: EPOXIDE HYDROLASE, ALPHA-BETA PROTEIN, LEUKOTRIENE BIOSYNTHESIS, METALLOPROTEASE, Inhibitor complex, Alternative splicing, Cytoplasm, Metal-binding, Multifunctional enzyme, Zinc
Deposited on 2008-03-10, released 2008-04-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.232
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d3chpa1, d3chpa2, d3chpa3
  • Heterogens: ZN, YB, ACT, IMD, 4BO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3chpA (A:)
peivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdlt
iekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltp
eqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpd
pedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesm
lkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishs
wtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgeth
pftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksit
tddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitake
ddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlr
lciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvta
mlvgkdlkvd

    Sequence, based on observed residues (ATOM records): (download) 
    >3chpA (A:)
ivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltie
kvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeq
tsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdpe
dpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlk
iaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswt
gnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpf
tklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittd
dwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakedd
lnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlc
iqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtaml
vgkdlkvd