PDB entry 3cbb

View 3cbb on RCSB PDB site
Description: Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product
Class: transcription/DNA
Keywords: zinc finger, protein-DNA complex, diabetes, TRANSCRIPTION-DNA COMPLEX
Deposited on 2008-02-21, released 2008-10-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-25, with a file datestamp of 2017-10-20.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Hepatocyte Nuclear Factor 4-alpha, DNA binding domain
  Species: Homo sapiens [TaxId:9606]
  Gene: HNF4A, HNF4, NR2A1, TCF14
  Database cross-references and differences (RAF-indexed):
  • Uniprot P41235 (0-End)
  Domains in SCOPe 2.07: d3cbba_
• Chain 'B':
  Compound: Hepatocyte Nuclear Factor 4-alpha, DNA binding domain
  Species: Homo sapiens [TaxId:9606]
  Gene: HNF4A, HNF4, NR2A1, TCF14
  Database cross-references and differences (RAF-indexed):
  • Uniprot P41235 (0-77)
  Domains in SCOPe 2.07: d3cbbb_
• Chain 'C':
  Compound: Hepatocyte Nuclear Factor 4-alpha promoter element DNA
  
• Chain 'D':
  Compound: Hepatocyte Nuclear Factor 4-alpha promoter element DNA
  
• Heterogens: ZN, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >3cbbA (A:)
  alcaicgdratgkhygasscdgckgffrrsvrknhmyscrfsrqcvvdkdkrnqcrycrl
  kkcfragmkkeavqnerd
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >3cbbA (A:)
  alcaicgdratgkhygasscdgckgffrrsvrknhmyscrfsrqcvvdkdkrnqcrycrl
  kkcfragmkkeavqne
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3cbbB (B:)
  alcaicgdratgkhygasscdgckgffrrsvrknhmyscrfsrqcvvdkdkrnqcrycrl
  kkcfragmkkeavqnerd
  

  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.