PDB entry 3bwy

View 3bwy on RCSB PDB site
Description: Crystal Structure of Human 108M Catechol O-methyltransferase bound with S-adenosylmethionine and inhibitor dinitrocatechol
Class: transferase
Keywords: COMT, methyltransferase, polymorphism, Rossmann fold, SAM, DNC
Deposited on 2008-01-10, released 2008-06-03
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.126
AEROSPACI score: 0.79 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: COMT protein
  Species: HOMO SAPIENS
  Gene: COMT
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6ICE6 (0-213)
  Domains in SCOPe 2.01: d3bwya_
• Heterogens: MG, SAM, DNC, MPD, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >3bwyA (A:)
  gdtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgkivdaviqehqpsv
  llelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagmkdkvtlvvgasqd
  iipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvicpgapdfla
  hvrgsscfecthyqsfleyrevvdglekaiykgp