PDB entry 3br3

View 3br3 on RCSB PDB site
Description: Crystal Structure of the Complex of Ethidium Bound to QacR(E90Q), a Mutant of a Multidrug Binding Transcriptional Repressor
Class: transcription
Keywords: QacR, multidrug resistance, TetR, ethidium, DNA-binding, Repressor, Transcription, Transcription regulation
Deposited on 2007-12-20, released 2008-12-23
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.222
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (71)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.03: d3br3a1, d3br3a2
  • Chain 'B':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (71)
      • engineered (89)
      • engineered (140)
    Domains in SCOPe 2.03: d3br3b1, d3br3b2
  • Heterogens: SO4, ET, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3br3A (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikaktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br3A (A:)
lkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskwq
eqwkseqikaktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnklenk
yidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqif
lngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3br3B (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikaktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br3B (B:)
kdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskwqe
qwkseqikaktnrekfylynelslttqyyyplqnaiiefyteyyktnsinekmnklenky
idayhvifkegnlngewsindvnavskiaanavngivtfteqnineriklmnkfsqifln
gls