PDB entry 3br0

View 3br0 on RCSB PDB site
Description: Crystal Structure of the Complex of Malachite Green Bound to QacR(E120Q), a Mutant of a Multidrug Binding Transcriptional Repressor
Class: transcription
Keywords: QacR, multidrug resistance, TetR, malachite green, DNA-binding, Plasmid, Repressor, Transcription, Transcription regulation
Deposited on 2007-12-20, released 2008-12-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2008-12-23, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.216
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (71)
      • engineered (119)
      • engineered (140)
    Domains in SCOPe 2.07: d3br0a1, d3br0a2
  • Chain 'B':
    Compound: HTH-type transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: qacR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N3
      • engineered (66)
      • engineered (71)
      • engineered (119)
      • engineered (140)
    Domains in SCOPe 2.07: d3br0b1, d3br0b2
  • Heterogens: SO4, MGR, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3br0A (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklq
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br0A (A:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkseqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklqn
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3br0B (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkseqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklq
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >3br0B (B:)
kdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskwqe
qwkseqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklqnky
idayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqifl
ngls