PDB entry 3a0i

View 3a0i on RCSB PDB site
Description: Human glucokinase in complex with a synthetic activator
Class: Transferase
Keywords: Glucokinase, Diabetes, Activator, Alternative splicing, ATP-binding, Diabetes mellitus, Disease mutation, Glycolysis, Kinase, Nucleotide-binding, Polymorphism, Transferase
Deposited on 2009-03-19, released 2009-04-28
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-06-23, with a file datestamp of 2009-06-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.229
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Glucokinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d3a0ix1, d3a0ix2
  • Heterogens: GLC, AJI, NA, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >3a0iX (X:)
taltlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegse
vgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyiseci
sdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaik
rrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegr
mcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlv
denllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrra
cesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrl
tpsceitfieseegsgrgaalvsavackkacmlgq

    Sequence, based on observed residues (ATOM records): (download) 
    >3a0iX (X:)
tlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegsevgd
flsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyisecisdf
ldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikrrg
dfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrmcv
ntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvden
llfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrraces
vstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrltps
ceitfieseegsgrgaalvsavackkac