PDB entry 2zxe

View 2zxe on RCSB PDB site
Description: Crystal structure of the sodium - potassium pump in the E2.2K+.Pi state
Class: hydrolase/transport protein
Keywords: membrane protein, ion pump, ATPase, K+ binding, Haloacid dehydrogenease superfamily, phosphate analogue, ATP-binding, Hydrolase, Ion transport, Nucleotide-binding, Phosphoprotein, HYDROLASE-TRANSPORT PROTEIN COMPLEX
Deposited on 2008-12-22, released 2009-05-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.248
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Na, K-ATPase alpha subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2zxea1, d2zxea2, d2zxea3, d2zxea4
  • Chain 'B':
    Compound: Na+,K+-ATPase beta subunit
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed):
    • PDB 2ZXE (Start-304)
    Domains in SCOPe 2.07: d2zxeb1, d2zxeb2
  • Chain 'G':
    Compound: Phospholemman-like protein
    Species: Squalus acanthias [TaxId:7797]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2zxeg_
  • Heterogens: MF4, MG, K, CLR, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zxeA (A:)
mgkgtasdkyepaatsenatkskkkgkkdkidkkrdldelkkevsmddhklsldelhnky
gtdltrgltnarakeilardgpnsltpppttpewikfcrqlfggfsillwigailcflay
giqaatedepandnlylgvvlstvvivtgcfsyyqeakssrimdsfknmvpqqalvirdg
ekstinaefvvagdlvevkggdripadlriisahgckvdnssltgesepqtrspefssen
pletrniaffstncvegtargvvvytgdrtvmgriatlasglevgrtpiaieiehfihii
tgvavflgvsffilslilgyswleavifligiivanvpegllatvtvcltltakrmarkn
clvknleavetlgststicsdktgtltqnrmtvahmwfdnqiheadttenqsgaafdkts
atwsalsriaalcnravfqagqdnvpilkrsvagdasesallkcielccgsvqgmrdrnp
kiveipfnstnkyqlsihenekssesryllvmkgaperildrcstillngaeeplkedmk
eafqnaylelgglgervlgfchfalpedkynegypfdadepnfpttdlcfvglmamidpp
raavpdavgkcrsagikvimvtgdhpitakaiakgvgiisegnetiediaarlnipigqv
nprdakacvvhgsdlkdlstevlddilhyhteivfartspqqkliivegcqrqgaivavt
gdgvndspalkkadigvamgisgsdvskqaadmillddnfasivtgveegrlifdnlkks
iaytltsnipeitpflvfiignvplplgtvtilcidlgtdmvpaislayeqaesdimkrq
prnpktdklvnerlismaygqigmiqalggffsyfvilaengflpmdligkrvrwddrwi
sdvedsfgqqwtyeqrkiveftchtsffisivvvqwadliicktrrnsifqqgmknkili
fglfeetalaaflsycpgtdvalrmyplkpswwfcafpysliiflydemrrfiirrspgg
wveqetyy

    Sequence, based on observed residues (ATOM records): (download) 
    >2zxeA (A:)
ldelkkevsmddhklsldelhnkygtdltrgltnarakeilardgpnsltpppttpewik
fcrqlfggfsillwigailcflaygiqaatedepandnlylgvvlstvvivtgcfsyyqe
akssrimdsfknmvpqqalvirdgekstinaefvvagdlvevkggdripadlriisahgc
kvdnssltgesepqtrspefssenpletrniaffstncvegtargvvvytgdrtvmgria
tlasglevgrtpiaieiehfihiitgvavflgvsffilslilgyswleavifligiivan
vpegllatvtvcltltakrmarknclvknleavetlgststicsdktgtltqnrmtvahm
wfdnqiheadttenqsgaafdktsatwsalsriaalcnravfqagqdnvpilkrsvagda
sesallkcielccgsvqgmrdrnpkiveipfnstnkyqlsihenekssesryllvmkgap
erildrcstillngaeeplkedmkeafqnaylelgglgervlgfchfalpedkynegypf
dadepnfpttdlcfvglmamidppraavpdavgkcrsagikvimvtgdhpitakaiakgv
giisegnetiediaarlnipigqvnprdakacvvhgsdlkdlstevlddilhyhteivfa
rtspqqkliivegcqrqgaivavtgdgvndspalkkadigvamgisgsdvskqaadmill
ddnfasivtgveegrlifdnlkksiaytltsnipeitpflvfiignvplplgtvtilcid
lgtdmvpaislayeqaesdimkrqprnpktdklvnerlismaygqigmiqalggffsyfv
ilaengflpmdligkrvrwddrwisdvedsfgqqwtyeqrkiveftchtsffisivvvqw
adliicktrrnsifqqgmknkilifglfeetalaaflsycpgtdvalrmyplkpswwfca
fpysliiflydemrrfiirrspggwveqetyy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2zxeB (B:)
margksketdggwkkflwdsekkeflgrtgsswfkiflfylifygclagifigtiqvlll
tlsdfepkyqdrvappglshapyaikteisfsisnpksyesfvksmhklmdlynessqag
nspfedcsdtpadyikrgdlddsqgqkkacrfsrmwlkncsglddttygyaegkpcvvak
lnriigfypkplknttdlpeelqanynqyvlplrcaakreedrekigsieyfglggyagf
plqyypyygkrlqkkylqpllaiqftnltqnmelrieckvygenidysekdrfrgrfevk
ievks

    Sequence, based on observed residues (ATOM records): (download) 
    >2zxeB (B:)
rtgsswfkiflfylifygclagifigtiqvllltlsdfepkyqdrvappglshapyaikt
eisfsisnpksyesfvksmhklmdlynessqagnspfedcsdtpadyikrgdlddsqgqk
kacrfsrmwlkncgyaegkpcvvaklnriigfypkplknttdlpeelqanynqyvlplrc
aarekigsieyfglggyagfplqyypyygkrlqkkylqpllaiqftnltqnmelrieckv
ygenidysekdrfrgrfevkievks

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2zxeG (G:)
mdpegpdnderftydyyrlrvvglivaavlcvigiiillagkcrckfnqnkrtrsnsgta
taqhllqpgeatec

    Sequence, based on observed residues (ATOM records): (download) 
    >2zxeG (G:)
egpdnderftydyyrlrvvglivaavlcvigiiillagk