PDB entry 2zr5

View 2zr5 on RCSB PDB site
Description: Crystal structure of a mutant PIN1 peptidyl-prolyl cis-trans isomerase
Class: isomerase
Keywords: PIN1 mutant (K63A), ISOMERASE, Cell cycle, Nucleus, Phosphoprotein, Rotamase
Deposited on 2008-08-22, released 2009-08-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-08-25, with a file datestamp of 2009-08-21.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.234
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PIN1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13526 (Start-162)
      • engineered (62)
    Domains in SCOPe 2.06: d2zr5a1, d2zr5a2
  • Heterogens: SO4, 1PG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zr5A (A:)
madeeklppgwekrmsrssgrvyyfnhitnasqwerpsgnsssggkngqgeparvrcshl
lvahsqsrrpsswrqekitrtkeealelingyiqkiksgeedfeslasqfsdcssakarg
dlgafsrgqmqkpfedasfalrtgemsgpvftdsgihiilrte

    Sequence, based on observed residues (ATOM records): (download) 
    >2zr5A (A:)
klppgwekrmsrssgrvyyfnhitnasqwerpsggkngqgeparvrcshllvahsqsrrp
sswrqekitrtkeealelingyiqkiksgeedfeslasqfsdcssakargdlgafsrgqm
qkpfedasfalrtgemsgpvftdsgihiilrte