PDB entry 2zgw
View 2zgw on RCSB PDB site
Description: Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Adenosine and Biotin, Mutations R48A and K111A
Class: ligase
Keywords: Biotin Biosynthesis, Dimer, LIGASE, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI
Deposited on
2008-01-28, released
2008-02-05
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.187
AEROSPACI score: 0.63
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: biotin--[acetyl-CoA-carboxylase] ligase
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: bpl
Database cross-references and differences (RAF-indexed):
- Uniprot O57883 (0-234)
- engineered (47)
- engineered (110)
Domains in SCOPe 2.04: d2zgwa1, d2zgwa2 - Chain 'B':
Compound: biotin--[acetyl-CoA-carboxylase] ligase
Species: Pyrococcus horikoshii [TaxId:70601]
Gene: bpl
Database cross-references and differences (RAF-indexed):
- Uniprot O57883 (0-234)
- engineered (47)
- engineered (110)
Domains in SCOPe 2.04: d2zgwb1, d2zgwb2 - Heterogens: ADN, BTN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2zgwA (A:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvslrfl
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2zgwB (B:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnrkwespeggl
wlsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegk
gdkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdiln
lvrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvslrfl
Sequence, based on observed residues (ATOM records): (download)
>2zgwB (B:)
mlglktsiigrrviyfqeitstnefaktsyleegtvivadkqtmghgalnkwespegglw
lsivlspkvpqkdlpkivflgavgvvetlkefsidgrikwpndvlvnykaiagvlvegkg
dkivlgiglnvnnkvpngatsmklelgsevpllsvfrslitnldrlylnflknpmdilnl
vrdnmilgvrvkilgdgsfegiaediddfgrliirldsgevkkviygdvslrfl