PDB entry 2zaz

View 2zaz on RCSB PDB site
Description: Crystal structure of P38 in complex with 4-anilino quinoline inhibitor
Class: Transferase
Keywords: Serine/threonine protein kinase, map kinase, P38, ATP-binding, Nucleotide-binding, Nucleus, Phosphorylation, Transferase
Deposited on 2007-10-12, released 2008-01-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.199
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2zaza_
  • Heterogens: ACT, GK1, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2zazA (A:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemt
gyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvg
tpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaa
qalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >2zazA (A:)
erptfyrqelnktiwevperyqnlspvggsvcaafdtktglrvavkklsrpfqsiihakr
tyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhv
qfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrw
yrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaell
kkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahay
faqyhdpddepvadpydqsfesrdllidewksltydevisfvppp