PDB entry 2yz3

View 2yz3 on RCSB PDB site
Description: Crystallographic Investigation of Inhibition Mode of the VIM-2 Metallo-beta-lactamase from Pseudomonas aeruginosa with Mercaptocarboxylate Inhibitor
Class: hydrolase
Keywords: metallo-beta-lactamase, enzyme-inhibitor complex, HYDROLASE
Deposited on 2007-05-02, released 2008-03-11
The last revision prior to the SCOP 1.75 freeze date was dated 2008-03-11, with a file datestamp of 2008-03-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.212
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: metallo-beta-lactamase
    Species: Pseudomonas putida
    Gene: VIM-2, bla VIM-2, blaVIM-2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2yz3a1
  • Chain 'B':
    Compound: metallo-beta-lactamase
    Species: Pseudomonas putida
    Gene: VIM-2, bla VIM-2, blaVIM-2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2yz3b1
  • Heterogens: ZN, SO4, M5P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yz3A (A:)
mfkllskllvyltasimaiasplafsvdssgeyptvseipvgevrlyqiadgvwshiatq
sfdgavypsnglivrdgdelllidtawgakntaallaeiekqiglpvtravsthfhddrv
ggvdvlraagvatyaspstrrlaevegneipthsleglsssgdavrfgpvelfypgaahs
tdnlvvyvpsasvlyggcaiyelsrtsagnvadadlaewptsieriqqhypeaqfvipgh
glpggldllkhttnvvkahtnrsvve

    Sequence, based on observed residues (ATOM records): (download) 
    >2yz3A (A:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yz3B (B:)
mfkllskllvyltasimaiasplafsvdssgeyptvseipvgevrlyqiadgvwshiatq
sfdgavypsnglivrdgdelllidtawgakntaallaeiekqiglpvtravsthfhddrv
ggvdvlraagvatyaspstrrlaevegneipthsleglsssgdavrfgpvelfypgaahs
tdnlvvyvpsasvlyggcaiyelsrtsagnvadadlaewptsieriqqhypeaqfvipgh
glpggldllkhttnvvkahtnrsvve

    Sequence, based on observed residues (ATOM records): (download) 
    >2yz3B (B:)
eyptvseipvgevrlyqiadgvwshiatqsfdgavypsnglivrdgdelllidtawgakn
taallaeiekqiglpvtravsthfhddrvggvdvlraagvatyaspstrrlaevegneip
thsleglsssgdavrfgpvelfypgaahstdnlvvyvpsasvlyggcaiyelsrtsagnv
adadlaewptsieriqqhypeaqfvipghglpggldllkhttnvv