PDB entry 2yob

View 2yob on RCSB PDB site
Description: High resolution AGXT_M structure
Class: transferase
Keywords: transferase, primary hyperoxaluria type I, agxt folding and stability defects
Deposited on 2012-10-22, released 2013-10-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-11-20, with a file datestamp of 2013-11-15.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.1713
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21549 (Start-387)
      • engineered mutation (339)
      • engineered mutation (384-387)
    Domains in SCOPe 2.08: d2yoba_
  • Chain 'B':
    Compound: Serine--pyruvate aminotransferase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P21549 (Start-387)
      • engineered mutation (339)
      • engineered mutation (384-387)
    Domains in SCOPe 2.08: d2yobb_
  • Heterogens: PLP, BTB, SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yobA (A:)
mashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdei
kegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerig
arvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykcll
lvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsf
yldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhg
rlqalglqlfvkdpalrlptvttvavpagydwrdivsyvmdhfdieimgglgpstgkvlr
igllgcnatrenvdrvtealraalvaqa

    Sequence, based on observed residues (ATOM records): (download) 
    >2yobA (A:)
hkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikeg
iqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarv
hpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvd
svaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyld
ikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlq
alglqlfvkdpalrlptvttvavpagydwrdivsyvmdhfdieimgglgpstgkvlrigl
lgcnatrenvdrvtealraalvaqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2yobB (B:)
mashkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdei
kegiqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerig
arvhpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykcll
lvdsvaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsf
yldikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhg
rlqalglqlfvkdpalrlptvttvavpagydwrdivsyvmdhfdieimgglgpstgkvlr
igllgcnatrenvdrvtealraalvaqa

    Sequence, based on observed residues (ATOM records): (download) 
    >2yobB (B:)
hkllvtppkallkplsipnqlllgpgpsnlpprimaagglqmigsmskdmyqimdeikeg
iqyvfqtrnpltlvisgsghcaleaalvnvlepgdsflvgangiwgqravdigerigarv
hpmtkdpgghytlqeveeglaqhkpvllflthgesstgvlqpldgfgelchrykclllvd
svaslggtplymdrqgidilysgsqkalnappgtslisfsdkakkkmysrktkpfsfyld
ikwlanfwgcddqprmyhhtipvislyslreslaliaeqglenswrqhreaaaylhgrlq
alglqlfvkdpalrlptvttvavpagydwrdivsyvmdhfdieimgglgpstgkvlrigl
lgcnatrenvdrvtealraalvaqa