PDB entry 2yir

View 2yir on RCSB PDB site
Description: structural analysis of checkpoint kinase 2 in complex with inhibitor pv1352
Class: transferase
Keywords: transferase, structure-based drug design
Deposited on 2011-05-16, released 2011-09-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-10-26, with a file datestamp of 2011-10-21.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.19666
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2yira_
  • Heterogens: YIR, NO3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2yirA (A:)
msvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsareadpal
nveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyf
yqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtp
tylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfi
pevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllseenestal
pqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >2yirA (A:)
svypkalrdeyimsktlgsgacgevklaferktckkvaikiisklnveteieilkklnhp
ciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengi
ihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtag
ynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlv
kkllvvdpkarftteealrhpwlqdedmkrkfqdllseenestalp