PDB entry 2yeh

View 2yeh on RCSB PDB site
Description: hsp90 inhibitors and drugs from fragment and virtual screening
Class: chaperone
Keywords: chaperone, stress response
Deposited on 2011-03-25, released 2011-06-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-06-29, with a file datestamp of 2011-06-24.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.21443
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2yeha_
  • Heterogens: SO4, 2KU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2yehA (A:)
    mghhhhhhhhhhssghiddadkhmdqpmeeeevetfafqaeiaqlmsliintfysnkeif
    lrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadli
    nnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawes
    saggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvek
    erdkevsddeae
    

    Sequence, based on observed residues (ATOM records): (download)
    >2yehA (A:)
    evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
    lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
    vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
    eyleerrikeivkkhsqfigypitlfvek