PDB entry 2yef
View 2yef on RCSB PDB site
Description: hsp90 inhibitors and drugs from fragment and virtual screening
Class: chaperone
Keywords: pu3, ATPase, chaperone, stress response, nucleotide-binding, ATP-binding, phosphoprotein, phosphorylation
Deposited on
2011-03-25, released
2011-06-15
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-06-29, with a file datestamp of
2011-06-24.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.17811
AEROSPACI score: 0.62
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d2yefa_ - Heterogens: MG, ANP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2yefA (A:)
mghhhhhhhhhhssghiddadkhmdqpmeeeevetfafqaeiaqlmsliintfysnkeif
lrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadli
nnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawes
saggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvek
erdkevsddeae
Sequence, based on observed residues (ATOM records): (download)
>2yefA (A:)
pmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskl
dsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadism
igqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhl
kedqteyleerrikeivkkhsqfigypitlfveker