PDB entry 2y5s

View 2y5s on RCSB PDB site
Description: Crystal structure of Burkholderia cenocepacia dihydropteroate synthase complexed with 7,8-dihydropteroate.
Class: transferase
Keywords: transferase, folate biosynthesis
Deposited on 2011-01-17, released 2011-01-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-04-25, with a file datestamp of 2012-04-20.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.17742
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydropteroate synthase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:95486]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B4E5F5 (Start-293)
      • cloning artifact (4)
    Domains in SCOPe 2.06: d2y5sa1, d2y5sa2
  • Chain 'B':
    Compound: dihydropteroate synthase
    Species: BURKHOLDERIA CENOCEPACIA [TaxId:95486]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B4E5F5 (Start-293)
      • cloning artifact (4)
    Domains in SCOPe 2.06: d2y5sb_
  • Heterogens: 78H, CL, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y5sA (A:)
ghmstflpaplqcgrfeltferplvmgilnatpdsfsdggrflarddalrraermiaega
dlldiggestrpgappvpldeelarviplvealrplnvplsidtykpavmraalaagadl
indiwgfrqpgaidavrdgnsglcamhmlgepqtmqvgepdygdvvtdvrdflaaraqal
rdagvaaericvdpgfgfgkavvddnyallaalpdtaparpdgraypilagmsrksmlga
viggkpplervaasvaaalcavergaaivrvhdvaatvdalsvwnavraaarqr

    Sequence, based on observed residues (ATOM records): (download) 
    >2y5sA (A:)
tflpaplqcgrfeltferplvmgilnatparddalrraermiaegadlldiggestrpga
ppvpldeelarviplvealrplnvplsidtykpavmraalaagadlindiwgfrqpgaid
avrdgnsglcamhmlgepqtmqvgepdygdvvtdvrdflaaraqalrdagvaaericvdp
gfgfgkavvddnyallaalpdtaparpdgraypilagmsrksmlgaviggkpplervaas
vaaalcavergaaivrvhdvaatvdalsvwnavraaarqr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2y5sB (B:)
ghmstflpaplqcgrfeltferplvmgilnatpdsfsdggrflarddalrraermiaega
dlldiggestrpgappvpldeelarviplvealrplnvplsidtykpavmraalaagadl
indiwgfrqpgaidavrdgnsglcamhmlgepqtmqvgepdygdvvtdvrdflaaraqal
rdagvaaericvdpgfgfgkavvddnyallaalpdtaparpdgraypilagmsrksmlga
viggkpplervaasvaaalcavergaaivrvhdvaatvdalsvwnavraaarqr

    Sequence, based on observed residues (ATOM records): (download) 
    >2y5sB (B:)
stflpaplqcgrfeltferplvmgilnatparddalrraermiaegadlldiggestrpg
appvpldeelarviplvealrplnvplsidtykpavmraalaagadlindiwgfrqpgai
davrdgnsglcamhmlgepqtmqvgepdygdvvtdvrdflaaraqalrdagvaaericvd
pgfgfgkavvddnyallaalpdtaparpdgraypilagmsrksmlgaviggkpplervaa
svaaalcavergaaivrvhdvaatvdalsvwnavraaarqr