PDB entry 2y2f

View 2y2f on RCSB PDB site
Description: crystal structure of yersinia pestis yoph in complex with an aminooxy-containing platform compound for inhibitor design
Class: hydrolase
Keywords: hydrolase, protein tyrosine phosphatase
Deposited on 2010-12-14, released 2011-03-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-09-28, with a file datestamp of 2011-09-23.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: 0.16685
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein-tyrosine phosphatase yoph
    Species: Yersinia pestis [TaxId:632]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7ARH8 (Start-305)
      • conflict (72)
      • conflict (229)
    Domains in SCOPe 2.06: d2y2fa_
  • Heterogens: YI1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2y2fA (A:)
mrerphtsghhgagearatapstvspygpearaelssrlttlrntlapatndprylqacg
geklnrfrdiqcrrqtavradlnanyiqvgntrtiacqyplqsqleshfrmlaenrtpvl
avlassseianqrfgmpdyfrqsgtygsitveskmtqqvglgdgimadmytltireagqk
tisvpvvhvgnwpdqtavssevtkalaslvdqtaetkrnmyeskgssavaddsklrpvih
cragvgrtaqligamcmndsrnsqlsvedmvsqmrvqrngimvqkdeqldvliklaegqg
rpllns

    Sequence, based on observed residues (ATOM records): (download) 
    >2y2fA (A:)
spygpearaelssrlttlrntlapatndprylqacggeklnrfrdiqcrrqtavradlna
nyiqvgntrtiacqyplqsqleshfrmlaenrtpvlavlassseianqrfgmpdyfrqsg
tygsitveskmtqqvglgdgimadmytltireagqktisvpvvhvgnwpdqtavssevtk
alaslvdqtaetkrnmyeskgssavaddsklrpvihcragvgrtaqligamcmndsrnsq
lsvedmvsqmrvqrngimvqkdeqldvliklaegqgrpllns