PDB entry 2xwn

View 2xwn on RCSB PDB site
Description: Crystal structure of IspD from Mycobacterium tuberculosis in complex with CTP and Mg
Class: transferase
Keywords: transferase, mep pathway
Deposited on 2010-11-04, released 2011-04-27
The last revision prior to the SCOPe 2.02 freeze date was dated 2012-02-01, with a file datestamp of 2012-01-27.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.21065
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96864 (Start-228)
      • expression tag (229-230)
    Domains in SCOPe 2.02: d2xwna_
  • Chain 'B':
    Compound: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96864 (Start-228)
      • expression tag (229-230)
    Domains in SCOPe 2.02: d2xwnb_
  • Heterogens: MG, CTP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xwnA (A:)
mvreagevvaivpaagsgerlavgvpkafyqldgqtlieravdglldsgvvdtvvvavpa
drtdearqilghramivaggsnrtdtvnlaltvlsgtaepefvlvhdaaraltppalvar
vvealrdgyaavvpvlplsdtikavdangvvlgtperaglravqtpqgfttdlllrsyqr
gsldlpaaeytddaslvehiggqvqvvdgdplafkittkldlllaqaivhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2xwnA (A:)
agevvaivpaagsgerlavgvpkafyqldgqtlieravdglldsgvvdtvvvavpadrtd
earqilghramivaggsnrtdtvnlaltvlsgtaepefvlvhdaaraltppalvarvvea
lrdgyaavvpvlplsdtikavdangvvlgtperaglravqtpqgfttdlllrsyqrgsey
tddaslvehiggqvqvvdgdplafkittkldlllaqaivhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xwnB (B:)
mvreagevvaivpaagsgerlavgvpkafyqldgqtlieravdglldsgvvdtvvvavpa
drtdearqilghramivaggsnrtdtvnlaltvlsgtaepefvlvhdaaraltppalvar
vvealrdgyaavvpvlplsdtikavdangvvlgtperaglravqtpqgfttdlllrsyqr
gsldlpaaeytddaslvehiggqvqvvdgdplafkittkldlllaqaivhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2xwnB (B:)
agevvaivpaagsgerlavgvpkafyqldgqtlieravdglldsgvvdtvvvavpadrtd
earqilghramivaggsnrtdtvnlaltvlsgtaepefvlvhdaaraltppalvarvvea
lrdgyaavvpvlplsdtikavdangvvlgtperaglravqtpqgfttdlllrsyqrgsld
lpaaeytddaslvehiggqvqvvdgdplafkittkldlllaqaivhh