PDB entry 2xwl

View 2xwl on RCSB PDB site
Description: Crystal structure of IspD from Mycobacterium smegmatis in complex with CTP and Mg
Class: transferase
Keywords: transferase, mep pathway
Deposited on 2010-11-04, released 2011-04-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:1772]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0R560 (Start-218)
      • expression tag (219-221)
    Domains in SCOPe 2.08: d2xwla1, d2xwla2
  • Chain 'B':
    Compound: 2-c-methyl-d-erythritol 4-phosphate cytidylyltransferase
    Species: MYCOBACTERIUM SMEGMATIS [TaxId:1772]
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0R560 (Start-218)
      • expression tag (219-222)
    Domains in SCOPe 2.08: d2xwlb1, d2xwlb2
  • Heterogens: MG, CTP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xwlA (A:)
matvavvpaagsgerlragrpkafvtlggtpllehalsglrasgvidriviavppaltde
sklvfggedsvivsggvdrtesvalaleaagdaefvlvhdaaraltppaliarvvaalke
ghsavvpglapadtikavdangavlgtperaglravqtpqgfhadvlrrayarataggvt
ddaslveqlgtpvqivdgdplafkittpldlvlaeavlahhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2xwlA (A:)
atvavvpaagsgerlragrpkafvtlggtpllehalsglrasgvidriviavppaltdes
klvfggedsvivsggvdrtesvalaleaagdaefvlvhdaaraltppaliarvvaalkeg
hsavvpglapadtikavdangavlgtperaglravqtpqgfhadvlrrayarataggvtd
daslveqlgtpvqivdgdplafkittpldlvlaeavlahhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xwlB (B:)
matvavvpaagsgerlragrpkafvtlggtpllehalsglrasgvidriviavppaltde
sklvfggedsvivsggvdrtesvalaleaagdaefvlvhdaaraltppaliarvvaalke
ghsavvpglapadtikavdangavlgtperaglravqtpqgfhadvlrrayarataggvt
ddaslveqlgtpvqivdgdplafkittpldlvlaeavlahhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2xwlB (B:)
atvavvpaagsgerlragrpkafvtlggtpllehalsglrasgvidriviavppaltdes
klvfggedsvivsggvdrtesvalaleaagdaefvlvhdaaraltppaliarvvaalkeg
hsavvpglapadtikavdangavlgtperaglravqtpqgfhadvlrrayarataggvtd
daslveqlgtpvqivdgdplafkittpldlvlaeavlahhhh