PDB entry 2xur

View 2xur on RCSB PDB site
Description: the g157c mutation in the escherichia coli sliding clamp specifically affects initiation of replication
Class: transferase
Keywords: replication, transferase, DNA-directed DNA polymerase
Deposited on 2010-10-20, released 2011-02-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-02-16, with a file datestamp of 2011-02-11.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.19673
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase III subunit beta
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A988 (7-372)
      • engineered mutation (163)
    Domains in SCOPe 2.08: d2xura1, d2xura2, d2xura3
  • Chain 'B':
    Compound: DNA polymerase III subunit beta
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A988 (7-End)
      • engineered mutation (163)
    Domains in SCOPe 2.08: d2xurb1, d2xurb2, d2xurb3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xurA (A:)
mhhhhhhmkftverehllkplqqvsgplggrptlpilgnlllqvadgtlsltgtdlemem
varvalvqphepgattvparkffdicrglpegaeiavqlegermlvrsgrsrfslstlpa
adfpnlddwqseveftlpqatmkrlieatqfsmahqdvryylncmlfetegeelrtvatd
ghrlavcsmpigqslpshsvivprkgvielmrmldggdnplrvqigsnnirahvgdfift
sklvdgrfpdyrrvlpknpdkhleagcdllkqafaraailsnekfrgvrlyvsenqlkit
annpeqeeaeeildvtysgaemeigfnvsyvldvlnalkcenvrmmltdsvssvqiedaa
sqsaayvvmpmrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2xurA (A:)
mkftverehllkplqqvsgplggrptlpilgnlllqvadgtlsltgtdlememvarvalv
qphepgattvparkffdicrglpegaeiavqlegermlvrsgrsrfslstlpaadfpnld
dwqseveftlpqatmkrlieatqfsmahqdvryylncmlfetegeelrtvatdghrlavc
smpigqslpshsvivprkgvielmrmldggdnplrvqigsnnirahvgdfiftsklvdgr
fpdyrrvlpknpdkhleagcdllkqafaraailsnekfrgvrlyvsenqlkitannpeqe
eaeeildvtysgaemeigfnvsyvldvlnalkcenvrmmltdsvssvqiedaasqsaayv
vmpmrl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xurB (B:)
mhhhhhhmkftverehllkplqqvsgplggrptlpilgnlllqvadgtlsltgtdlemem
varvalvqphepgattvparkffdicrglpegaeiavqlegermlvrsgrsrfslstlpa
adfpnlddwqseveftlpqatmkrlieatqfsmahqdvryylncmlfetegeelrtvatd
ghrlavcsmpigqslpshsvivprkgvielmrmldggdnplrvqigsnnirahvgdfift
sklvdgrfpdyrrvlpknpdkhleagcdllkqafaraailsnekfrgvrlyvsenqlkit
annpeqeeaeeildvtysgaemeigfnvsyvldvlnalkcenvrmmltdsvssvqiedaa
sqsaayvvmpmrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2xurB (B:)
mkftverehllkplqqvsgplggrptlpilgnlllqvadgtlsltgtdlememvarvalv
qphepgattvparkffdicrglpegaeiavqlegermlvrsgrsrfslstlpaadfpnld
dwqseveftlpqatmkrlieatqfsmahqdvryylncmlfetegeelrtvatdghrlavc
smpigqslpshsvivprkgvielmrmldggdnplrvqigsnnirahvgdfiftsklvdgr
fpdyrrvlpknpdkhleagcdllkqafaraailsnekfrgvrlyvsenqlkitannpeqe
eaeeildvtysgaemeigfnvsyvldvlnalkcenvrmmltdsvssvqiedaasqsaayv
vmpm