PDB entry 2xin

View 2xin on RCSB PDB site
Description: protein engineering of xylose (glucose) isomerase from actinoplanes missouriensis. 1. crystallography and site-directed mutagenesis of metal binding sites
Class: isomerase(intramolecular oxidoreductse)
Keywords: isomerase(intramolecular oxidoreductse)
Deposited on 1992-04-06, released 1993-07-15
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.154
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12851 (Start-392)
      • conflict (288)
    Domains in SCOPe 2.04: d2xina_
  • Chain 'B':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12851 (Start-392)
      • conflict (288)
    Domains in SCOPe 2.04: d2xinb_
  • Chain 'C':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12851 (Start-392)
      • conflict (288)
    Domains in SCOPe 2.04: d2xinc_
  • Chain 'D':
    Compound: d-xylose isomerase
    Species: Actinoplanes missouriensis [TaxId:1866]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12851 (Start-392)
      • conflict (288)
    Domains in SCOPe 2.04: d2xind_
  • Heterogens: SOR, CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2xinA (A:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xinA (A:)
vqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfg
sdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrq
mdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiep
kpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklf
hidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedyd
gvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrs
afedydadavgakgfgfvklnqlaiehllgar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2xinB (B:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xinB (B:)
vqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfg
sdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrq
mdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiep
kpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklf
hidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedyd
gvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrs
afedydadavgakgfgfvklnqlaiehllgar

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2xinC (C:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xinC (C:)
vqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfg
sdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrq
mdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiep
kpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklf
hidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedyd
gvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrs
afedydadavgakgfgfvklnqlaiehllgar

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2xinD (D:)
svqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpf
gsdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlr
qmdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaie
pkpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkkl
fhidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedy
dgvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladr
safedydadavgakgfgfvklnqlaiehllgar

    Sequence, based on observed residues (ATOM records): (download) 
    >2xinD (D:)
vqatredkfsfglwtvgwqardafgdatrtaldpveavhklaeigaygitfhdddlvpfg
sdaqtrdgiiagfkkaldetglivpmvttnlfthpvfkdggftsndrsvrryairkvlrq
mdlgaelgaktlvlwggregaeydsakdvsaaldryrealnllaqysedrgyglrfaiep
kpneprgdillptaghaiafvqelerpelfginpetgheqmsnlnftqgiaqalwhkklf
hidlngqhgpkfdqdlvfghgdllnafslvdllengpdgapaydgprnfdykpsrtedyd
gvwesakanirmylllkerakafradpevqealaaskvaelktptlnpgegyaelladrs
afedydadavgakgfgfvklnqlaiehllgar