PDB entry 2xds

View 2xds on RCSB PDB site
Description: Structure of HSP90 with small molecule inhibitor bound
Class: chaperone
Keywords: chaperone
Deposited on 2010-05-07, released 2010-09-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-04-24, with a file datestamp of 2013-04-19.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: 0.2097
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2xdsa_
  • Heterogens: DMS, MT0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2xdsA (A:)
    mgsshhhhhhssglvprgshmdqpmeeeevetfafqaeiaqlmsliintfysnkeiflre
    lisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtkadlinnl
    gtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqyawessag
    gsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitlfvekerd
    kevsddeae
    

    Sequence, based on observed residues (ATOM records): (download)
    >2xdsA (A:)
    vetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
    hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfgv
    gfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqte
    yleerrikeivkkhsqfigypitlfve