PDB entry 2x4z

View 2x4z on RCSB PDB site
Description: crystal structure of the human p21-activated kinase 4 in complex with pf-03758309
Class: transferase
Keywords: transferase, nucleotide-binding ATP-binding, phosphoprotein
Deposited on 2010-02-03, released 2010-05-19
The last revision prior to the SCOPe 2.04 freeze date was dated 2010-06-02, with a file datestamp of 2010-05-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.2
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase pak 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O96013
      • engineered mutation (3)
    Domains in SCOPe 2.04: d2x4za_
  • Heterogens: GOL, X4Z, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2x4zA (A:)
gshmsheqfraalqlvvdpgdprsyldnfikigegstgivciatvrssgklvavkkmdlr
kqqrrellfnevvimrdyqhenvvemynsylvgdelwvvmefleggaltdivthtrmnee
qiaavclavlqalsvlhaqgvihrdiksdsillthdgrvklsdfgfcaqvskevprrksl
vgtpywmapelisrlpygpevdiwslgimviemvdgeppyfnepplkamkmirdnlpprl
knlhkvspslkgfldrllvrdpaqrataaellkhpflakagppasivplmrqnrtr

    Sequence, based on observed residues (ATOM records): (download) 
    >2x4zA (A:)
msheqfraalqlvvdpgdprsyldnfikigegstgivciatvrssgklvavkkmdlrkqq
rrellfnevvimrdyqhenvvemynsylvgdelwvvmefleggaltdivthtrmneeqia
avclavlqalsvlhaqgvihrdiksdsillthdgrvklsdfgfcaqvskevprrkslvgt
pywmapelisrlpygpevdiwslgimviemvdgeppyfnepplkamkmirdnlpprlknl
hkvspslkgfldrllvrdpaqrataaellkhpflakagppasivplmrqnrt