PDB entry 2wfh

View 2wfh on RCSB PDB site
Description: the human slit 2 dimerization domain d4
Class: splicing
Keywords: developmental protein, neurogenesis, splicing, glycoprotein, leucine-rich repeat, disulfide bond, differentiation, egf-like domain, id14-eh4, roundabout, chemotaxis, nerve cell, midline, heparan, heparin, secreted, guidance, d4, xds, lrr, slit, axon, neuron, phaser, sulfate
Deposited on 2009-04-06, released 2009-04-21
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-09-28, with a file datestamp of 2011-09-23.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.18599
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: slit homolog 2 protein c-product
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WFH
    • Uniprot O94813 (Start-183)
    Domains in SCOPe 2.07: d2wfha_
  • Chain 'B':
    Compound: slit homolog 2 protein c-product
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WFH
    • Uniprot O94813 (Start-183)
    Domains in SCOPe 2.07: d2wfhb_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2wfhA (A:)
gsrcptectcldtvvrcsnkglkvlpkgiprdvtelyldgnqftlvpkelsnykhltlid
lsnnristlsnqsfsnmtqlltlilsynrlrcipprtfdglkslrllslhgndisvvpeg
afndlsalshlaiganplycdcnmqwlsdwvkseykepgiarcagpgemadklllttpsk
kftcaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wfhA (A:)
cptectcldtvvrcsnkglkvlpkgiprdvtelyldgnqftlvpkelsnykhltlidlsn
nristlsnqsfsnmtqlltlilsynrlrcipprtfdglkslrllslhgndisvvpegafn
dlsalshlaiganplycdcnmqwlsdwvkseykepgiarcagpgemadklllttpskkft
c

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2wfhB (B:)
gsrcptectcldtvvrcsnkglkvlpkgiprdvtelyldgnqftlvpkelsnykhltlid
lsnnristlsnqsfsnmtqlltlilsynrlrcipprtfdglkslrllslhgndisvvpeg
afndlsalshlaiganplycdcnmqwlsdwvkseykepgiarcagpgemadklllttpsk
kftcaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2wfhB (B:)
cptectcldtvvrcsnkglkvlpkgiprdvtelyldgnqftlvpkelsnykhltlidlsn
nristlsnqsfsnmtqlltlilsynrlrcipprtfdglkslrllslhgndisvvpegafn
dlsalshlaiganplycdcnmqwlsdwvkseykepgiarcagpgemadklllttpskkft
c