PDB entry 2we2

View 2we2 on RCSB PDB site
Description: ebv dutpase double mutant gly78asp-asp131ser with dump
Class: hydrolase
Keywords: dutpase, monomer, hydrolase, herpes virus, epstein-barr virus, nucleotide metabolism
Deposited on 2009-03-27, released 2009-07-07
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-09-15, with a file datestamp of 2009-09-11.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.196
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyuridine 5'-triphosphate nucleotidohydrolase
    Species: HUMAN HERPESVIRUS 4 [TaxId:10377]
    Database cross-references and differences (RAF-indexed):
    • PDB 2WE2
      • engineered mutation (85)
      • engineered mutation (138)
    • Uniprot P03195
    Domains in SCOPe 2.03: d2we2a1, d2we2a2
  • Heterogens: SO4, UMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2we2A (A:)
gamgsgipmeacphiryafqndklllqqasvgrltlvnkttillrpmktttvdlglyarp
peghglmlwgstsrpvtshvgiidpdytgelrlilqnqrrynstlrpselkihlaafrya
tpqmeedkgpinhpqypgsvgldvslpkdlalfphqtvsvtltvpppsiphhrptifgrs
glamqgilvkpcrwrrggvdvsltnfsdqtvflnkyrrfcqlvylhkhhltsfysphsda
gvlgprslfrwasctfeevpslamgdsglsealegrqgrgfgssgq

    Sequence, based on observed residues (ATOM records): (download) 
    >2we2A (A:)
cphiryafqndklllqqasvgrltlvnkttillrpmktttvdlglyarppeghglmlwgs
tsrpvtshvgiidpdytgelrlilqnqrrynstlrpselkihlaafryatpqgpinhpqy
pgsvgldvslpkdlalfphqtvsvtltvpppsiphhrptifgrsglamqgilvkpcrwrr
ggvdvsltnfsdqtvflnkyrrfcqlvylhkhhltsfysphsdagvlgprslfrwasctf
eevpslam