PDB entry 2w6n

View 2w6n on RCSB PDB site
Description: crystal structure of biotin carboxylase from e. coli in complex with amino-oxazole fragment series
Class: ligase
Keywords: ligase, ATP-binding, fatty acid biosynthesis, nucleotide-binding, lipid synthesis, ATP-grasp domain, fragment screening
Deposited on 2008-12-18, released 2009-05-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-04-27, with a file datestamp of 2011-04-22.
Experiment type: XRAY
Resolution: 1.87 Å
R-factor: 0.177
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: biotin carboxylase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w6na1, d2w6na2, d2w6na3
  • Chain 'B':
    Compound: biotin carboxylase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2w6nb1, d2w6nb2, d2w6nb3
  • Heterogens: OA2, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w6nA (A:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglqek

    Sequence, based on observed residues (ATOM records): (download) 
    >2w6nA (A:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2w6nB (B:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklglqek

    Sequence, based on observed residues (ATOM records): (download) 
    >2w6nB (B:)
mldkivianrgeialrilrackelgiktvavhssadrdlkhvlladetvcigpapsvksy
lnipaiisaaeitgavaihpgygflsenanfaeqversgfifigpkaetirlmgdkvsai
aamkkagvpcvpgsdgplgddmdknraiakrigypviikasgggggrgmrvvrgdaelaq
sismtraeakaafsndmvymekylenprhveiqvladgqgnaiylaerdcsmqrrhqkvv
eeapapgitpelrryigercakacvdigyrgagtfeflfengefyfiemntriqvehpvt
emitgvdlikeqlriaagqplsikqeevhvrghavecrinaedpntflpspgkitrfhap
ggfgvrweshiyagytvppyydsmigklicygenrdvaiarmknalqeliidgiktnvdl
qirimndenfqhggtnihylekklg