PDB entry 2w22

View 2w22 on RCSB PDB site
Description: Activation Mechanism of Bacterial Thermoalkalophilic Lipases
Class: hydrolase
Keywords: thermoalkalophilic lipases, hydrolase, open conformation, activation mechanism
Deposited on 2008-10-23, released 2008-12-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-02-28, with a file datestamp of 2018-02-23.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triacylglycerol lipase
    Species: GEOBACILLUS THERMOCATENULATUS [TaxId:33938]
    Database cross-references and differences (RAF-indexed):
    • PDB 2W22
      • conflict (354)
    • Uniprot Q59260 (1-388)
    Domains in SCOPe 2.08: d2w22a_
  • Heterogens: CA, ZN, EGC, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2w22A (A:)
masprandapivllhgftgwgreemlgfkywggvrgdieqwlndngyrtytlavgplssn
wdraceayaqlvggtvdygaahaakhgharfgrtypgllpelkrggrvhiiahsqggqta
rmlvsllengsqeereyakahnvslsplfegghhfvlsvttiatphdgttlvnmvdftdr
ffdlqkavlkaaavasnvpytsqvydfkldqwglrrqpgesfdhyferlkrspvwtstdt
arydlsipgaeklnqwvqaspntyylsfsterthrgaltgnyypelgmnafsavvcapfl
gsyrnealgiddrwlendgivntvsmngpkrgssdrivpydgtlkkgvwndmgtynvdhl
evigvdpnpsfdirafylrlaeqlaslrp

    Sequence, based on observed residues (ATOM records): (download) 
    >2w22A (A:)
asprandapivllhgftgwgreemlgfkywggvrgdieqwlndngyrtytlavgplssnw
draceayaqlvggtvdygaahaakhgharfgrtypgllpelkrggrvhiiahsqggqtar
mlvsllengsqeereyakahnvslsplfegghhfvlsvttiatphdgttlvnmvdftdrf
fdlqkavlkaaavasnvpytsqvydfkldqwglrrqpgesfdhyferlkrspvwtstdta
rydlsipgaeklnqwvqaspntyylsfsterthrgaltgnyypelgmnafsavvcapflg
syrnealgiddrwlendgivntvsmngpkrgssdrivpydgtlkkgvwndmgtynvdhle
vigvdpnpsfdirafylrlaeqlaslrp