PDB entry 2vvc
View 2vvc on RCSB PDB site
Description: aminopyrrolidine factor xa inhibitor
Class: hydrolase
Keywords: hydrolase, zymogen, protease, glycoprotein, gamma-carboxyglutamic acid, blood clotting, coagulation factor, hydroxylation, serine protease, egf-like domain
Deposited on
2008-06-05, released
2009-07-07
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-31.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.203
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: activated factor xa heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00742 (0-End)
- engineered mutation (137)
Domains in SCOPe 2.04: d2vvca_ - Chain 'B':
Compound: activated factor xa heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00742 (0-End)
- engineered mutation (137)
Domains in SCOPe 2.04: d2vvcb_ - Chain 'K':
Compound: factor x light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2vvck_ - Chain 'L':
Compound: factor x light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d2vvcl_ - Heterogens: LZF, CA, NA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vvcA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
k
Sequence, based on observed residues (ATOM records): (download)
>2vvcA (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2vvcB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
k
Sequence, based on observed residues (ATOM records): (download)
>2vvcB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgggeav
hevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlmtqktgivs
gfgrthekgeqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqedacqgdsggp
hvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
- Chain 'K':
Sequence, based on SEQRES records: (download)
>2vvcK (K:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr
Sequence, based on observed residues (ATOM records): (download)
>2vvcK (K:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtler
- Chain 'L':
Sequence, based on SEQRES records: (download)
>2vvcL (L:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtlerr
Sequence, based on observed residues (ATOM records): (download)
>2vvcL (L:)
klcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle