PDB entry 2vpi
View 2vpi on RCSB PDB site
Description: Human GMP synthetase - glutaminase domain
Class: ligase
Keywords: guanine monophosphate synthetase, phosphoprotein, gmp synthetase, gmp biosynthesis, glutamine amidotransferase, gmps, ligase, cytoplasm, ATP-binding, proto-oncogene, glutaminase domain, nucleotide-binding, purine biosynthesis, chromosomal rearrangement
Deposited on
2008-02-29, released
2008-03-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-03-07, with a file datestamp of
2018-03-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: GMP synthase
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2VPI (Start-22)
- Uniprot P49915 (23-217)
Domains in SCOPe 2.08: d2vpia1, d2vpia2 - Chain 'B':
Compound: GMP synthase
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2VPI (Start-22)
- Uniprot P49915 (23-217)
Domains in SCOPe 2.08: d2vpib1, d2vpib2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2vpiA (A:)
mhhhhhhssgvdlgtenlyfqsmegavvildagaqygkvidrrvrelfvqseifpletpa
faikeqgfraiiisggpnsvyaedapwfdpaiftigkpvlgicygmqmmnkvfggtvhkk
svredgvfnisvdntcslfrglqkeevvllthgdsvdkvadgfkvvarsgnivagianes
kklygaqfhpevgltengkvilknflydiagcsgtftv
Sequence, based on observed residues (ATOM records): (download)
>2vpiA (A:)
megavvildagaqygkvidrrvrelfvqseifpletpafaikeqgfraiiisgapwfdpa
iftigkpvlgicygmqmmnkvfggtvhkksvredgvfnisvdntcslfrglqkeevvllt
hgdsvdkvadgfkvvarsgnivagianeskklygaqfhpevgltengkvilknflydiag
csgtftv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2vpiB (B:)
mhhhhhhssgvdlgtenlyfqsmegavvildagaqygkvidrrvrelfvqseifpletpa
faikeqgfraiiisggpnsvyaedapwfdpaiftigkpvlgicygmqmmnkvfggtvhkk
svredgvfnisvdntcslfrglqkeevvllthgdsvdkvadgfkvvarsgnivagianes
kklygaqfhpevgltengkvilknflydiagcsgtftv
Sequence, based on observed residues (ATOM records): (download)
>2vpiB (B:)
megavvildagaqygkvidrrvrelfvqseifpletpafaikeqgfraiiisgpwfdpai
ftigkpvlgicygmqmmnkvfggtvhkksvredgvfnisvdntcslfrglqkeevvllth
gdsvdkvadgfkvvarsgnivagianeskklygaqfhpevgltengkvilknflydiagc
sgtftv