PDB entry 2vl2

View 2vl2 on RCSB PDB site
Description: Oxidized and reduced forms of human peroxiredoxin 5
Class: oxidoreductase
Keywords: thioredoxin peroxidase, alternative initiation, antioxidant enzyme, redox-active center, cytoplasm, peroxidase, peroxisome, antioxidant, polymorphism, mitochondrion, peroxiredoxin, oxidoreductase, transit peptide, thioredoxin fold
Deposited on 2008-01-08, released 2008-08-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.93 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: peroxiredoxin-5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL2 (Start-10)
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.08: d2vl2a2, d2vl2a3
  • Chain 'B':
    Compound: peroxiredoxin-5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL2
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.08: d2vl2b_
  • Chain 'C':
    Compound: peroxiredoxin-5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VL2
    • Uniprot P30044 (11-171)
    Domains in SCOPe 2.08: d2vl2c_
  • Heterogens: BEZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2vl2A (A:)
    rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
    thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
    lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vl2A (A:)
    sapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqa
    ealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsi
    fgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2vl2B (B:)
    rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
    thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
    lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vl2B (B:)
    apikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqae
    alkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsif
    gnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2vl2C (C:)
    rgshhhhhhgsapikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcsk
    thlpgfveqaealkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketd
    lllddslvsifgnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql
    

    Sequence, based on observed residues (ATOM records): (download)
    >2vl2C (C:)
    apikvgdaipavevfegepgnkvnlaelfkgkkgvlfgvpgaftpgcskthlpgfveqae
    alkakgvqvvaclsvndafvtgewgrahkaegkvrlladptgafgketdlllddslvsif
    gnrrlkrfsmvvqdgivkalnvepdgtgltcslapniisql