PDB entry 2v9w

View 2v9w on RCSB PDB site
Description: complex structure of sulfolobus solfataricus dpo4 and DNA duplex containing a hydrophobic thymine isostere 2,4-difluorotoluene nucleotide in the template strand
Class: transferase
Keywords: DNA-directed DNA polymerase, p2 DNA polymerase IV, nucleotidyltransferase, mutator protein, DNA replication, 4-difluorotoluene, DNA repair, DNA-binding, transferase, metal-binding, translesion DNA polymerase, ddctp, cytoplasm, magnesium, DNA damage
Deposited on 2007-08-27, released 2007-10-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.218
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V9W (6-23)
    • Uniprot Q97W02 (6-End)
    Domains in SCOPe 2.07: d2v9wa1, d2v9wa2
  • Chain 'B':
    Compound: DNA polymerase IV
    Species: SULFOLOBUS SOLFATARICUS [TaxId:273057]
    Database cross-references and differences (RAF-indexed):
    • PDB 2V9W (6-23)
    • Uniprot Q97W02 (6-End)
    Domains in SCOPe 2.07: d2v9wb1, d2v9wb2
  • Chain 'C':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *cp*tp*g)-3'
  • Chain 'D':
    Compound: 5'-d(*tp*tp*cp*ap*gp*dftp*ap*gp*tp*cp*cp *tp*tp*cp*cp*cp*cp*c)-3'
  • Chain 'E':
    Compound: 5'-d(*gp*gp*gp*gp*gp*ap*ap*gp*gp*ap *cp*tp*g)-3'
  • Chain 'F':
    Compound: 5'-d(*tp*tp*cp*ap*gp*dftp*ap*gp*tp*cp*cp *tp*tp*cp*cp*cp*cp*c)-3'
  • Heterogens: CA, DCT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2v9wA (A:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2v9wA (A:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfieai

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2v9wB (B:)
hhhhhhmivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfg
vkagipiveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdk
vrdyreaynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrl
ireldiadvpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeyn
epirtrvrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedld
ivsrgrtfphgisketaysesvkllqkileederkirrigvrfskfieaigldkffdt

    Sequence, based on observed residues (ATOM records): (download) 
    >2v9wB (B:)
mivlfvdfdyfyaqveevlnpslkgkpvvvcvfsgrfedsgavatanyearkfgvkagip
iveakkilpnavylpmrkevyqqvssrimnllreysekieiasideayldisdkvrdyre
aynlgleiknkilekekitvtvgisknkvfakiaadmakpngikviddeevkrlireldi
advpgignitaeklkklginklvdtlsiefdklkgmigeakakylislardeynepirtr
vrksigrivtmkrnsrnleeikpylfraieesyykldkripkaihvvavtedldivsrgr
tfphgisketaysesvkllqkileederkirrigvrfskfiea

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.