PDB entry 2v9t
View 2v9t on RCSB PDB site
Description: Complex between the second LRR domain of Slit2 and The first Ig domain from Robo1
Class: structural protein/receptor
Keywords: structural protein-receptor complex, developmental protein, ig domain, roundabout, chemotaxis, lrr domain, immunoglobulin domain, leucine-rich repeat, neuronal development, phosphorylation, egf-like domain, disease mutation, slit2, ligand, membrane, secreted, receptor, neurogenesis, glycoprotein, transmembrane, proto-oncogene, differentiation structural protein/receptor, complex
Deposited on
2007-08-25, released
2007-09-25
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-08-29, with a file datestamp of
2012-08-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.188
AEROSPACI score: 0.54
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: roundabout homolog 1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2V9T
- engineered mutation (101)
- Uniprot Q9Y6N7 (2-107)
Domains in SCOPe 2.08: d2v9ta_ - Chain 'B':
Compound: slit homolog 2 protein n-product
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 2V9T
- Uniprot O94813 (2-End)
Domains in SCOPe 2.08: d2v9tb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2v9tA (A:)
gslrqedfpprivehpsdlivskgepatlnckaegrptptiewykggervetdkddprsh
rmllpsgslfflrivhgrksrpdegvyvcvarnylgeavshdaslevaaaahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2v9tA (A:)
slrqedfpprivehpsdlivskgepatlnckaegrptptiewykggervetdkddprshr
mllpsgslfflrivhgrksrpdegvyvcvarnylgeavshdasleva
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2v9tB (B:)
gslhcpaactcsnnivdcrgkglteiptnlpetiteirleqntikvippgafspykklrr
idlsnnqiselapdafqglrslnslvlygnkitelpkslfeglfslqllllnankinclr
vdafqdlhnlnllslydnklqtiakgtfsplraiqtmhlaqnpficdchlkwladylhtn
pietsgarctsprrlankrigqikskkfrcsaaahhhhhh
Sequence, based on observed residues (ATOM records): (download)
>2v9tB (B:)
gslhcpaactcsnnivdcrgkglteiptnlpetiteirleqntikvippgafspykklrr
idlsnnqiselapdafqglrslnslvlygnkitelpkslfeglfslqllllnankinclr
vdafqdlhnlnllslydnklqtiakgtfsplraiqtmhlaqnpficdchlkwladylhtn
pietsgarctsprrlankrigqikskkfrc