PDB entry 2uvn

View 2uvn on RCSB PDB site
Description: Crystal structure of econazole-bound CYP130 from Mycobacterium tuberculosis
Class: oxidoreductase
Keywords: iron, heme, monooxygenase, metal-binding, oxidoreductase
Deposited on 2007-03-12, released 2007-12-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-08-01, with a file datestamp of 2012-07-27.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.2
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 130
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q11062 (Start-411)
      • expression tag (412-413)
    Domains in SCOPe 2.07: d2uvna1, d2uvna2
  • Chain 'B':
    Compound: cytochrome p450 130
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2uvnb_
  • Heterogens: HEM, ECN, F, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2uvnA (A:)
mhhhhhhmtsvmshefqlataetwpnpwpmyralrdhdpvhhvvppqrpeydyyvlsrha
dvwsaardhqtfssaqgltvnygelemiglhdtppmvmqdppvhtefrklvsrgftprqv
etveptvrkfvverleklrangggdivtelfkplpsmvvahylgvpeedwtqfdgwtqai
vaanavdgattgaldavgsmmayftglierrrtepaddaishlvaagvgadgdtagtlsi
laftftmvtggndtvtgmlggsmpllhrrpdqrrlllddpegipdaveellrltspvqgl
artttrdvtigdttipagrrvlllygsanrderqygpdaaeldvtrcprniltfshgahh
clgaaaarmqcrvaltellarcpdfevaesrivwsggsyvrrplsvpfrvtssr

    Sequence, based on observed residues (ATOM records): (download) 
    >2uvnA (A:)
shefqlataetwpnpwpmyralrdhdpvhhvvppqrpeydyyvlsrhadvwsaardhqtf
ssaqgltvnygelemiglhdtppmvmqdppvhtefrklvsrgftprqvetveptvrkfvv
erleklrangggdivtelfkplpsmvvahylgvpeedwtqfdgwtqaivaangattgald
avgsmmayftglierrrtepaddaishlvaagvgadgdtagtlsilaftftmvtggndtv
tgmlggsmpllhrrpdqrrlllddpegipdaveellrltspvqglartttrdvtigdtti
pagrrvlllygsanrderqygpdaaeldvtrcprniltfshgahhclgaaaarmqcrval
tellarcpdfevaesrivwsggsyvrrplsvpfrvtssr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2uvnB (B:)
mhhhhhhmtsvmshefqlataetwpnpwpmyralrdhdpvhhvvppqrpeydyyvlsrha
dvwsaardhqtfssaqgltvnygelemiglhdtppmvmqdppvhtefrklvsrgftprqv
etveptvrkfvverleklrangggdivtelfkplpsmvvahylgvpeedwtqfdgwtqai
vaanavdgattgaldavgsmmayftglierrrtepaddaishlvaagvgadgdtagtlsi
laftftmvtggndtvtgmlggsmpllhrrpdqrrlllddpegipdaveellrltspvqgl
artttrdvtigdttipagrrvlllygsanrderqygpdaaeldvtrcprniltfshgahh
clgaaaarmqcrvaltellarcpdfevaesrivwsggsyvrrplsvpfrvtssr

    Sequence, based on observed residues (ATOM records): (download) 
    >2uvnB (B:)
hefqlataetwpnpwpmyralrdhdpvhhvvppqrpeydyyvlsrhadvwsaardhqtfs
saqgltvnygelemiglhdtppmvmqdppvhtefrklvsrgftprqvetveptvrkfvve
rleklrangggdivtelfkplpsmvvahylgvpeedwtqfdgwtqaivattgaldavgsm
mayftglierrrtepaddaishlvaagvgadgdtagtlsilaftftmvtggndtvtgmlg
gsmpllhrrpdqrrlllddpegipdaveellrltspvqglartttrdvtigdttipagrr
vlllygsanrderqygpdaaeldvtrcprniltfshgahhclgaaaarmqcrvaltella
rcpdfevaesrivwsggsyvrrplsvpfrvts