PDB entry 2r0n

View 2r0n on RCSB PDB site
Description: The effect of a Glu370Asp mutation in Glutaryl-CoA Dehydrogenase on Proton Transfer to the Dienolate Intermediate
Class: oxidoreductase
Keywords: Glutaryl-CoA Dehydrogenase, Flavoprotein, Isomerase, Alternative splicing, Disease mutation, FAD, Mitochondrion, Oxidoreductase, Polymorphism, Transit peptide
Deposited on 2007-08-20, released 2008-04-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.219
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutaryl-CoA dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2r0na1, d2r0na2
  • Heterogens: FAD, TGC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r0nA (A:)
rpefdwqdplvleeqlttdeilirdtfrtycqerlmprillanrnevfhreiisemgelg
vlgptikgygcagvssvaygllarelervdsgyrsamsvqsslvmhpiyaygseeqrqky
lpqlakgellgcfgltepnsgsdpssmetrahynssnksytlngtktwitnspmadlfvv
warcedgcirgfllekgmrglsapriqgkfslrasatgmiimdgvevpeenvlpgasslg
gpfgclnnarygiawgvlgasefclhtarqyaldrmqfgvplarnqliqkkladmlteit
lglhaclqlgrlkdqdkaapemvsllkrnncgkaldiarqardmlggngisdeyhvirha
mnleavntyegthdihalilgraitgiqaftask

    Sequence, based on observed residues (ATOM records): (download) 
    >2r0nA (A:)
efdwqdplvleeqlttdeilirdtfrtycqerlmprillanrnevfhreiisemgelgvl
gptikgygcagvssvaygllarelervdsgyrsamsvqsslvmhpiyaygseeqrqkylp
qlakgellgcfgltepnsgsdpssmetrahynssnksytlngtktwitnspmadlfvvwa
rcedgcirgfllekgmrglsapriqgkfslrasatgmiimdgvevpeenvlpgasslggp
fgclnnarygiawgvlgasefclhtarqyaldrmqfgvplarnqliqkkladmlteitlg
lhaclqlgrlkdqdkaapemvsllkrnncgkaldiarqardmlggngisdeyhvirhamn
leavntyegthdihalilgraitgiqafta