PDB entry 2r09

View 2r09 on RCSB PDB site
Description: Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
Class: signaling protein
Keywords: autoinhibition, Grp1, PIP3, Arf, 3-phosphoinositide, Pleckstrin Homology Domain, Guanine-nucleotide releasing factor, SIGNALING PROTEIN
Deposited on 2007-08-17, released 2007-12-04
The last revision prior to the SCOPe 2.04 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.206
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytohesin-3
    Species: Mus musculus [TaxId:10090]
    Gene: Pscd3, Grp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O08967 (10-End)
      • expression tag (1-9)
      • engineered (15)
      • engineered (207)
    Domains in SCOPe 2.04: d2r09a1, d2r09a2
  • Chain 'B':
    Compound: Cytohesin-3
    Species: Mus musculus [TaxId:10090]
    Gene: Pscd3, Grp1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O08967 (10-End)
      • expression tag (1-9)
      • engineered (15)
      • engineered (207)
    Domains in SCOPe 2.04: d2r09b1, d2r09b2
  • Heterogens: SO4, 4IP, PGE, PE5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2r09A (A:)
mghhhhhhgsttqrnaqiamgrkkfnmdpkkgiqfliendllqsspedvaqflykgegln
ktvigdylgerddfnikvlqafvelhefadlnlvqalrqflwsfrlpgeaqkidrmmeaf
asryclcnpgvfqstdtcyvlsfaiimlntslhnhnvrdkptaerfitmnrgineggdlp
eellrnlyesiknepfkipeddgndltytffnpdregwllklggrvktwkrrwfiltdnc
lyyfeyttdkeprgiiplenlsirevedprkpncfelynpshkgqvikackteadgrvve
gnhvvyrisapspeekeewmksikasisrdpfydmlatrkrriankk

    Sequence, based on observed residues (ATOM records): (download) 
    >2r09A (A:)
ghhhhhhgsttqrnaqiamgrkkfnmdpkkgiqfliendllqsspedvaqflykgeglnk
tvigdylgerddfnikvlqafvelhefadlnlvqalrqflwsfrlpgeaqkidrmmeafa
sryclcnpgvfqstdtcyvlsfaiimlntslhnhnvrdkptaerfitmnrgineggdlpe
ellrnlyesiknepfkipeddgndltytffnpdregwllklggrvktwkrrwfiltdncl
yyfeyttdkeprgiiplenlsirevedprkpncfelynpshkgqvikackteadgrvveg
nhvvyrisapspeekeewmksikasisrdpfydmlatrkrria

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2r09B (B:)
mghhhhhhgsttqrnaqiamgrkkfnmdpkkgiqfliendllqsspedvaqflykgegln
ktvigdylgerddfnikvlqafvelhefadlnlvqalrqflwsfrlpgeaqkidrmmeaf
asryclcnpgvfqstdtcyvlsfaiimlntslhnhnvrdkptaerfitmnrgineggdlp
eellrnlyesiknepfkipeddgndltytffnpdregwllklggrvktwkrrwfiltdnc
lyyfeyttdkeprgiiplenlsirevedprkpncfelynpshkgqvikackteadgrvve
gnhvvyrisapspeekeewmksikasisrdpfydmlatrkrriankk

    Sequence, based on observed residues (ATOM records): (download) 
    >2r09B (B:)
ghhhhhhgsttqrnaqiamgrkkfnmdpkkgiqfliendllqsspedvaqflykgeglnk
tvigdylgerddfnikvlqafvelhefadlnlvqalrqflwsfrlpgeaqkidrmmeafa
sryclcnpgvfqstdtcyvlsfaiimlntslhnhnvrdkptaerfitmnrgineggdlpe
ellrnlyesiknepfkipeddgndltytffnpdregwllklggrvktwkrrwfiltdncl
yyfeyttdkeprgiiplenlsirevedprkpncfelynpshkgqvikackteadgrvveg
nhvvyrisapspeekeewmksikasisrdpfydmlatrkrr