PDB entry 2quj

View 2quj on RCSB PDB site
Description: Crystal structures of human tryptophanyl-tRNA synthetase in complex with TrpAMP
Class: ligase
Keywords: aminoacyl-tRNA synthetase, Rossmann fold, induced-fit mechnism, ATP-binding, Ligase, Nucleotide-binding, Protein biosynthesis
Deposited on 2007-08-05, released 2008-04-29
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.214
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophanyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS, IFI53, WRS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23381 (Start-470)
      • expression tag (471-474)
    Domains in SCOPe 2.01: d2quja1
  • Chain 'B':
    Compound: Tryptophanyl-tRNA synthetase
    Species: Homo sapiens [TaxId:9606]
    Gene: WARS, IFI53, WRS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d2qujb1
  • Heterogens: CL, TYM, TRP, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qujA (A:)
mpnsepasllelfnsiatqgelvrslkagnaskdeidsavkmlvslkmsykaaagedyka
dcppgnpaptsnhgpdateaeedfvdpwtvqtssakgidydklivrfgsskidkelinri
eratgqrphhflrrgiffshrdmnqvldayenkkpfylytgrgpsseamhvghlipfift
kwlqdvfnvplviqmtddekylwkdltldqaysyavenakdiiacgfdinktfifsdldy
mgmssgfyknvvkiqkhvtfnqvkgifgftdsdcigkisfpaiqaapsfsnsfpqifrdr
tdiqclipcaidqdpyfrmtrdvaprigypkpallhstffpalqgaqtkmsasdpnssif
ltdtakqiktkvnkhafsggrdtieehrqfggncdvdvsfmyltffledddkleqirkdy
tsgamltgelkkalievlqpliaehqarrkevtdeivkefmtprklsfdfqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2qujA (A:)
wtvqtssakgidydklivrfgsskidkelinrieratgqrphhflrrgiffshrdmnqvl
dayenkkpfylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdlt
ldqaysyavenakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgif
gftdsdcigkisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvapri
gypkpallhstffpalqgaqtkmsasdpnssifltdtakqiktkvnkhafsggrdtieeh
rqfggncdvdvsfmyltffledddkleqirkdytsgamltgelkkalievlqpliaehqa
rrkevtdeivkefmtprklsfdfqhhhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qujB (B:)
mpnsepasllelfnsiatqgelvrslkagnaskdeidsavkmlvslkmsykaaagedyka
dcppgnpaptsnhgpdateaeedfvdpwtvqtssakgidydklivrfgsskidkelinri
eratgqrphhflrrgiffshrdmnqvldayenkkpfylytgrgpsseamhvghlipfift
kwlqdvfnvplviqmtddekylwkdltldqaysyavenakdiiacgfdinktfifsdldy
mgmssgfyknvvkiqkhvtfnqvkgifgftdsdcigkisfpaiqaapsfsnsfpqifrdr
tdiqclipcaidqdpyfrmtrdvaprigypkpallhstffpalqgaqtkmsasdpnssif
ltdtakqiktkvnkhafsggrdtieehrqfggncdvdvsfmyltffledddkleqirkdy
tsgamltgelkkalievlqpliaehqarrkevtdeivkefmtprklsfdfqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2qujB (B:)
sakgidydklivrfgsskidkelinrieratgqrphhflrrgiffshrdmnqvldayenk
kpfylytgrgpsseamhvghlipfiftkwlqdvfnvplviqmtddekylwkdltldqays
yavenakdiiacgfdinktfifsdldymgmssgfyknvvkiqkhvtfnqvkgifgftdsd
cigkisfpaiqaapsfsnsfpqifrdrtdiqclipcaidqdpyfrmtrdvaprigypkpa
llhstffpalqgaqtkmsasdpnssifltdtakqiktkvnkhafsggrdtieehrqfggn
cdvdvsfmyltffledddkleqirkdytsgamltgelkkalievlqpliaehqarrkevt
deivkefmtprklsfdfq