PDB entry 2qk7

View 2qk7 on RCSB PDB site
Description: A covalent S-F heterodimer of staphylococcal gamma-hemolysin
Class: toxin
Keywords: pore-forming toxin, beta-barrel, protein-protein interaction, molecular plasticity, covalent complex, Cytolysis, Hemolysis, Secreted, TOXIN
Deposited on 2007-07-10, released 2008-02-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.182
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gamma-hemolysin component A
    Species: Staphylococcus aureus subsp. aureus [TaxId:196620]
    Gene: hlgA, hlg2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A074
      • engineered (35)
      • see remark 999 (224)
    Domains in SCOPe 2.07: d2qk7a_
  • Chain 'B':
    Compound: Gamma-hemolysin component B
    Species: Staphylococcus aureus subsp. aureus [TaxId:196620]
    Gene: hlgB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A077 (Start-306)
      • see remark 999 (63)
      • see remark 999 (70-71)
      • engineered (163)
    Domains in SCOPe 2.07: d2qk7b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2qk7A (A:)
gplgspefenkiedigqgaeiikrtqditskrlaicqniqfdfvkdkkynkdalvvkmqg
fissrttysdlkkypyikrmiwpfqynislktkdsnvdlinylpknkidsadvsqklgyn
iggnfqsapsiggsgsfnysktisynqknyvtevesqnskgvkwgvkansfvtpngqvsa
ydqylfaqdptgpaardyfvpdnqlppliqsgfnpsfittlshekgkgdksefeitygrn
mdatyayvtrhrlavdrkhdafknrnvtvkyevnwkthevkiksitpk

    Sequence, based on observed residues (ATOM records): (download) 
    >2qk7A (A:)
aeiikrtqditskrlaicqniqfdfvkdkkynkdalvvkmqgfissrttysdlikrmiwp
fqynislktkdsnvdlinylpknkidsadvsqklgyniggnfqsapsiggsgsfnyskti
synqknyvtevesqnskgvkwgvkansfvtpqvsaydqylfaqdptgpaardyfvpdnql
ppliqsgfnpsfittlshekgkgdksefeitygrnmdatyayvtrlavdrkhdafknrnv
tvkyevnwkthevkiksit

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2qk7B (B:)
gplgspefegkitpvsvkkvddkvtlykttatadsdkfkisqiltfnfikdksydkdtlv
lkaagninsgyekpnpndydfsklywgakynvsissqsndsvnvvdyapknqneefqvqn
tlgytfggdisisnglsgglngntafsetinykqesyrttlsrctnyknvgwgveahkim
nngwgpygrdsfhptygnelflagrqssayagqnfiaqhqmpllsrsnfnpeflsvlshr
qdgakkskitvtyqremdlyqirwngfywaganyknfktrtfkstyeidwenhkvklldt
ketennk

    Sequence, based on observed residues (ATOM records): (download) 
    >2qk7B (B:)
kitpvsvkkvddkvtlykttatadsdkfkisqiltfnfikdksydkdtlvlkaagninsg
yekpnpndydfsklywgakynvsissqsndsvnvvdyapknqneefqvqntlgytfggdi
sisngltafsetinykqesyrttlsrctnyknvgwgveahkimnngwgpygrdsfhptyg
nelflagrayagqnfiaqhqmpllsrsnfnpeflsvlshrqdgakkskitvtyqremdly
qirwngfywaganyknfktrtfkstyeidwenhkvklldtketennk