PDB entry 2pqp

View 2pqp on RCSB PDB site
Description: Crystal structure of human HDAC7 in complex with Trichostatin A (TSA)
Class: hydrolase
Keywords: HDAC, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2007-05-02, released 2007-05-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2008-02-19, with a file datestamp of 2008-02-15.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.182
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 7a
    Species: HOMO SAPIENS
    Gene: HDAC7A, HDAC7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2pqpa_
  • Chain 'B':
    Compound: Histone deacetylase 7a
    Species: HOMO SAPIENS
    Gene: HDAC7A, HDAC7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2pqpb_
  • Chain 'C':
    Compound: Histone deacetylase 7a
    Species: HOMO SAPIENS
    Gene: HDAC7A, HDAC7
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2pqpc_
  • Heterogens: ZN, K, TSN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pqpA (A:)
raqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsrhp
ehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkldng
klagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkngfa
vvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyqdp
svlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafrivv
mpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlalegg
hdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqrla
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2pqpA (A:)
tlpfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasl
eelqsvhserhvllygtnplsrlkldngklagllaqrmfvmlpcggvgvdtdtiwnelhs
snaarwaagsvtdlafkvasrelkngfavvrppghhadhstamgfcffnsvaiacrqlqq
qskaskilivdwdvhhgngtqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgeg
fnvnvawaggldppmgdpeylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyh
vsakcfgymtqqlmnlaggavvlalegghdltaicdaseacvaallgnrvdplseegwkq
kpnlnairsleavirvhskywgcmqr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pqpB (B:)
raqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsrhp
ehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkldng
klagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkngfa
vvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyqdp
svlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafrivv
mpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlalegg
hdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqrla
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2pqpB (B:)
lpfttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasle
elqsvhserhvllygtnplsvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkva
srelkngfavvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgng
tqqtfyqdpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpe
ylaafrivvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlagg
avvlalegghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhsk
ywgcmqrl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pqpC (C:)
raqsspaapaslsapepasqarvlsssetpartlpfttgliydsvmlkhqcscgdnsrhp
ehagriqsiwsrlqerglrsqceclrgrkasleelqsvhserhvllygtnplsrlkldng
klagllaqrmfvmlpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkngfa
vvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyqdp
svlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafrivv
mpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlalegg
hdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmqrla
s

    Sequence, based on observed residues (ATOM records): (download) 
    >2pqpC (C:)
ttgliydsvmlkhqcscgdnsrhpehagriqsiwsrlqerglrsqceclrgrkasleelq
svhserhvllygtnplpcggvgvdtdtiwnelhssnaarwaagsvtdlafkvasrelkng
favvrppghhadhstamgfcffnsvaiacrqlqqqskaskilivdwdvhhgngtqqtfyq
dpsvlyislhrhddgnffpgsgavdevgagsgegfnvnvawaggldppmgdpeylaafri
vvmpiarefspdlvlvsagfdaaeghpaplggyhvsakcfgymtqqlmnlaggavvlale
gghdltaicdaseacvaallgnrvdplseegwkqkpnlnairsleavirvhskywgcmq