PDB entry 2pf4

View 2pf4 on RCSB PDB site
Description: Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit
Class: hydrolase regulator/viral protein
Keywords: PP2A, SV40, small t, DnaJ, Aalpha subunit, HYDROLASE REGULATOR-VIRAL PROTEIN COMPLEX
Deposited on 2007-04-03, released 2007-08-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-05-22, with a file datestamp of 2013-05-17.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.247
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Mus musculus [TaxId:10090]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pf4a_
  • Chain 'B':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Mus musculus [TaxId:10090]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pf4b_
  • Chain 'C':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Mus musculus [TaxId:10090]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pf4c_
  • Chain 'D':
    Compound: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform
    Species: Mus musculus [TaxId:10090]
    Gene: PPP2R1A
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2pf4d_
  • Chain 'E':
    Compound: Small T antigen
    Species: Simian virus 40 [TaxId:10633]
    Gene: small t antigen
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Small T antigen
    Species: Simian virus 40 [TaxId:10633]
    Gene: small t antigen
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Small T antigen
    Species: Simian virus 40 [TaxId:10633]
    Gene: small t antigen
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Small T antigen
    Species: Simian virus 40 [TaxId:10633]
    Gene: small t antigen
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pf4A (A:)
maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
aashkvkefcenlsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdn
tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

    Sequence, based on observed residues (ATOM records): (download) 
    >2pf4A (A:)
iavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevllalaeq
lgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahfvplv
krlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaasklgef
akvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptlrqaa
edkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvkefcen
lsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdntiehllplflaq
lkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieympllag
qlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvlamsgd
pnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkigpild
nstlqsevkpilekltqdqdvdvkyfaqealtvls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pf4B (B:)
maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
aashkvkefcenlsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdn
tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

    Sequence, based on observed residues (ATOM records): (download) 
    >2pf4B (B:)
vlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevllalaeqlg
tfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahfvplvkr
laggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaasklgefak
vleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptlrqaaed
kswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvkefcenls
adcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdntiehllplflaqlk
decpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieympllagql
gveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvlamsgdpn
ylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkigpildns
tlqsevkpilekltqdqdvdvkyfaqealtvlsla

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pf4C (C:)
maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
aashkvkefcenlsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdn
tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

    Sequence, based on observed residues (ATOM records): (download) 
    >2pf4C (C:)
iavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevllalaeq
lgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahfvplv
krlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaasklgef
akvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptlrqaa
edkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvkefcen
lsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdntiehllplflaq
lkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieympllag
qlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvlamsgd
pnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkigpild
nstlqsevkpilekltqdqdvdvkyfaqealtvlsla

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2pf4D (D:)
maaadgddslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiy
dedevllalaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehs
psdleahfvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpm
vrraaasklgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedl
ealvmptlrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevra
aashkvkefcenlsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdn
tiehllplflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvr
laiieympllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewaha
tiipkvlamsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnv
akslqkigpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

    Sequence, based on observed residues (ATOM records): (download) 
    >2pf4D (D:)
iavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevllalaeq
lgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleahfvplv
krlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaasklgef
akvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmptlrqaa
edkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvkefcen
lsadcrenvimtqilpcikelvsdanqhvksalasvimglspilgkdntiehllplflaq
lkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieympllag
qlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvlamsgd
pnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqkigpild
nstlqsevkpilekltqdqdvdvkyfaqealtvlsla

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.