PDB entry 2pd3

View 2pd3 on RCSB PDB site
Description: Crystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
Class: oxidoreductase
Keywords: antibacterial target, Helicobacter pylori, type II fatty acid biosynthesis, enoyl-ACP-reductase, fabI, OXIDOREDUCTASE
Deposited on 2007-03-31, released 2007-04-17
The last revision prior to the SCOP 1.75 freeze date was dated 2008-06-24, with a file datestamp of 2008-06-20.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.233
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Helicobacter pylori [TaxId:210]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pd3a1
  • Chain 'B':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Helicobacter pylori [TaxId:210]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pd3b1
  • Chain 'C':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Helicobacter pylori [TaxId:210]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pd3c1
  • Chain 'D':
    Compound: Enoyl-[acyl-carrier-protein] reductase [NADH]
    Species: Helicobacter pylori [TaxId:210]
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2pd3d1
  • Heterogens: NAD, TCL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2pd3A (A:)
mgflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyv
yeldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisv
yslieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhh
irvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvs
gevhfvdagyhvmgmgaveekdnkatllwdlhkeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pd3A (A:)
gflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyvy
eldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisvy
slieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhhi
rvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvsg
evhfvdagyhvmgmgaveekdnkatllwdlhkeq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2pd3B (B:)
mgflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyv
yeldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisv
yslieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhh
irvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvs
gevhfvdagyhvmgmgaveekdnkatllwdlhkeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pd3B (B:)
gflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyvy
eldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisvy
slieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhhi
rvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvsg
evhfvdagyhvmgmgaveekdnkatllwdlhkeq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2pd3C (C:)
mgflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyv
yeldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisv
yslieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhh
irvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvs
gevhfvdagyhvmgmgaveekdnkatllwdlhkeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pd3C (C:)
gflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyvy
eldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisvy
slieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhhi
rvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvsg
evhfvdagyhvmgmgaveekdnkatllwdlhkeq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2pd3D (D:)
mgflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyv
yeldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisv
yslieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhh
irvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvs
gevhfvdagyhvmgmgaveekdnkatllwdlhkeq

    Sequence, based on observed residues (ATOM records): (download) 
    >2pd3D (D:)
gflkgkkglivgvannksiaygiaqscfnqgatlaftylneslekrvrpiaqelnspyvy
eldvskeehfkslynsvkkdlgsldfivhsvafapkealegslletsksafntameisvy
slieltntlkpllnngasvltlsylgstkymahynvmglakaalesavrylavdlgkhhi
rvnalsagpirtlassgiadfrmilkwneinaplrknvsleevgnagmyllsslssgvsg
evhfvdagyhvmgmgaveekdnkatllwdlhkeq