PDB entry 2ovx
View 2ovx on RCSB PDB site
Description: MMP-9 active site mutant with barbiturate inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: MATRIX METALLOPROTEINASE, S1-PRIME POCKET, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
2007-02-15, released
2007-06-19
The last revision prior to the SCOPe 2.02 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.217
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Matrix metalloproteinase-9 (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB)
Species: Homo sapiens [TaxId:9606]
Gene: MMP9, CLG4B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2ovxa_ - Chain 'B':
Compound: Matrix metalloproteinase-9 (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB)
Species: Homo sapiens [TaxId:9606]
Gene: MMP9, CLG4B
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d2ovxb_ - Heterogens: ZN, CA, CL, 4MR, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>2ovxA (A:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>2ovxB (B:)
fegdlkwhhhnitywiqnysedlpraviddafarafalwsavtpltftrvysrdadiviq
fgvaehgdgypfdgkdgllahafppgpgiqgdahfdddelwslgkgqgyslflvaahqfg
halgldhssvpealmypmyrftegpplhkddvngirhly