PDB entry 2obi

View 2obi on RCSB PDB site
Description: Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4)
Class: Oxidoreductase
Keywords: HUMAN GPX4, PEROXIDASE, SELENOPROTEIN, THIOREDOXIN-FOLD, ANTI-OXIDATVE DEFENSE SYSTEM, Oxidoreductase
Deposited on 2006-12-19, released 2007-09-18
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.165
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phospholipid hydroperoxide glutathione peroxidase (GPX4)
    Species: Homo sapiens [TaxId:9606]
    Gene: GPX4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2obia_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2obiA (A:)
mrgshhhhhhgsaccasrddwrcarsmhefsakdidghmvnldkyrgfvcivtnvasqcg
ktevnytqlvdlharyaecglrilafpcnqfgkqepgsneeikefaagynvkfdmfskic
vngddahplwkwmkiqpkgkgilgnaikwnftkflidkngcvvkrygpmeeplviekdlp
hyf

    Sequence, based on observed residues (ATOM records): (download) 
    >2obiA (A:)
ddwrcarsmhefsakdidghmvnldkyrgfvcivtnvasqcgktevnytqlvdlharyae
cglrilafpcnqfgkqepgsneeikefaagynvkfdmfskicvngddahplwkwmkiqpk
gkgilgnaikwnftkflidkngcvvkrygpmeeplviekdlphyf