PDB entry 2nyt

View 2nyt on RCSB PDB site
Description: The APOBEC2 Crystal Structure and Functional Implications for AID
Class: hydrolase
Keywords: cytidine deaminase, zinc-ion binding, APOBEC, HYDROLASE
Deposited on 2006-11-21, released 2007-01-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.246
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable C->U-editing enzyme APOBEC-2
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y235 (6-189)
      • cloning artifact (1-5)
    Domains in SCOPe 2.08: d2nyta1, d2nyta2
  • Chain 'B':
    Compound: Probable C->U-editing enzyme APOBEC-2
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y235 (6-189)
      • cloning artifact (0-5)
    Domains in SCOPe 2.08: d2nytb1, d2nytb2
  • Chain 'C':
    Compound: Probable C->U-editing enzyme APOBEC-2
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y235 (6-189)
      • cloning artifact (5)
    Domains in SCOPe 2.08: d2nytc1, d2nytc2
  • Chain 'D':
    Compound: Probable C->U-editing enzyme APOBEC-2
    Species: Homo sapiens [TaxId:9606]
    Gene: APOBEC2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y235 (6-189)
      • cloning artifact (5)
    Domains in SCOPe 2.08: d2nytd1, d2nytd2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2nytA (A:)
gsgggmivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledeh
aaahaeeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrl
fmweepeiqaalkklkeagcklrimkpqdfeyvwqnfveqeegeskafqpwediqenfly
yeekladilk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nytA (A:)
sgggmivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledeha
aahaeeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrlf
mweepeiqaalkklkeagcklrimkpqdfeyvwqnfveqeeafqpwediqenflyyeekl
adilk

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2nytB (B:)
gsgggmivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledeh
aaahaeeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrl
fmweepeiqaalkklkeagcklrimkpqdfeyvwqnfveqeegeskafqpwediqenfly
yeekladilk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2nytC (C:)
gsgggmivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledeh
aaahaeeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrl
fmweepeiqaalkklkeagcklrimkpqdfeyvwqnfveqeegeskafqpwediqenfly
yeekladilk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nytC (C:)
mivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledehaaaha
eeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrlfmwee
peiqaalkklkeagcklrimkpqdfeyvwqnfveqeegeskafqpwediqenflyyeekl
adilk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2nytD (D:)
gsgggmivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledeh
aaahaeeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrl
fmweepeiqaalkklkeagcklrimkpqdfeyvwqnfveqeegeskafqpwediqenfly
yeekladilk

    Sequence, based on observed residues (ATOM records): (download) 
    >2nytD (D:)
mivtgerlpanffkfqfrnveyssgrnktflcyvveaqgkggqvqasrgyledehaaaha
eeaffntilpafdpalrynvtwyvssspcaacadriiktlsktknlrllilvgrlfmwee
peiqaalkklkeagcklrimkpqdfeyvwqnfveqefqpwediqenflyyeekladilk